ID E9EXC5_METRA Unreviewed; 566 AA.
AC E9EXC5;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Prenylcysteine oxidase {ECO:0000313|EMBL:EFY99745.1};
GN ORFNames=MAA_04674 {ECO:0000313|EMBL:EFY99745.1};
OS Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium
OS anisopliae (strain ARSEF 23)).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=655844 {ECO:0000313|EMBL:EFY99745.1, ECO:0000313|Proteomes:UP000002498};
RN [1] {ECO:0000313|EMBL:EFY99745.1, ECO:0000313|Proteomes:UP000002498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA Wang C.;
RT "Genome sequencing and comparative transcriptomics of the model
RT entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL PLoS Genet. 7:E1001264-E1001264(2011).
RN [2] {ECO:0000313|EMBL:EFY99745.1, ECO:0000313|Proteomes:UP000002498}
RP GENOME REANNOTATION.
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the prenylcysteine oxidase family.
CC {ECO:0000256|ARBA:ARBA00009967}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFY99745.1}.
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DR EMBL; ADNJ02000001; EFY99745.1; -; Genomic_DNA.
DR RefSeq; XP_007820961.1; XM_007822770.1.
DR AlphaFoldDB; E9EXC5; -.
DR GeneID; 19258960; -.
DR KEGG; maj:MAA_04674; -.
DR HOGENOM; CLU_021176_0_0_1; -.
DR OrthoDB; 1334100at2759; -.
DR Proteomes; UP000002498; Unassembled WGS sequence.
DR GO; GO:0001735; F:prenylcysteine oxidase activity; IEA:InterPro.
DR GO; GO:0030328; P:prenylcysteine catabolic process; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR010795; Prenylcys_lyase.
DR InterPro; IPR017046; Prenylcysteine_Oxase.
DR PANTHER; PTHR15944; FARNESYLCYSTEINE LYASE; 1.
DR PANTHER; PTHR15944:SF0; PRENYLCYS_LYASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13450; NAD_binding_8; 1.
DR Pfam; PF07156; Prenylcys_lyase; 1.
DR PIRSF; PIRSF036292; Prenylcysteine_oxidase; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..566
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003235716"
FT DOMAIN 143..522
FT /note="Prenylcysteine lyase"
FT /evidence="ECO:0000259|Pfam:PF07156"
FT REGION 523..566
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 566 AA; 61944 MW; 91B1D0CD91AEB073 CRC64;
MHLPLLKLVA LATAAAAAAR DATNHPRRVK EVKNVAVIGA GAAGTSAAYH LQKYAEEEGL
AVNITVFEKT DHIGGRTVTV NAFNDPGQPV ELGASIFIKD NHIMYNATRD FDLSLTGLTE
PQPADYTAIW DGETILFRSE AGASKWWDAA KLFLKYGLAP YRAVQLVKSA VGTFLRLYET
PYFPFRSLTQ RAFELGLLRL TGVTGEQYLR DNNINPDFVR DLMQSATRVN YASNMAYIHG
LEAMVSFSTE GAVAVAGGNW QIFEKLLQHS GAAYYPNTSV AALAFQKGTD KPGSTPKYLI
STKSSGSKSK AAKLPTAFDN VIIASPWQFS GIEAAKGVIK HRIDTIPYMK LHVTLFTSPF
LLQPSFFGLE AGTKAPSNVY TTLGKDEEAH EGPEGVGRTG FYSISTLRTV TNPKTQGKEF
LYKIFSAEPV NSTFLSDILG TPVPSCFISN ETTGEVEPIS WYYPHWFYSY PIESPRVTFQ
DPIVGRGLYY TSGVESFIST METSALMGMN VARLMADDFA GVTRSRGGNK DTASQDTSPR
PPREDFWDSM DSEMGASMNF PGAHEL
//
