ID E9F547_METRA Unreviewed; 807 AA.
AC E9F547;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Zinc finger domain-containing protein {ECO:0000313|EMBL:EFY97100.1};
GN ORFNames=MAA_07396 {ECO:0000313|EMBL:EFY97100.1};
OS Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium
OS anisopliae (strain ARSEF 23)).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=655844 {ECO:0000313|EMBL:EFY97100.1, ECO:0000313|Proteomes:UP000002498};
RN [1] {ECO:0000313|EMBL:EFY97100.1, ECO:0000313|Proteomes:UP000002498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA Wang C.;
RT "Genome sequencing and comparative transcriptomics of the model
RT entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL PLoS Genet. 7:E1001264-E1001264(2011).
RN [2] {ECO:0000313|EMBL:EFY97100.1, ECO:0000313|Proteomes:UP000002498}
RP GENOME REANNOTATION.
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFY97100.1}.
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DR EMBL; ADNJ02000003; EFY97100.1; -; Genomic_DNA.
DR RefSeq; XP_007823585.1; XM_007825394.1.
DR AlphaFoldDB; E9F547; -.
DR GeneID; 19261682; -.
DR KEGG; maj:MAA_07396; -.
DR HOGENOM; CLU_007230_0_0_1; -.
DR OrthoDB; 206729at2759; -.
DR Proteomes; UP000002498; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd04813; PA_1; 1.
DR CDD; cd16454; RING-H2_PA-TM-RING; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22765; RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR22765:SF483; RING FINGER PROTEIN MUG145; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 531..551
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 667..710
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 165..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 309..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 425..514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 582..647
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 720..807
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 452..468
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 582..624
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 732..747
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..768
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 807 AA; 86793 MW; 01E687ECB5D2911B CRC64;
MRTPRVAILV FFFAAFLFIV FRALTATRTT VVASYPPAPR TSSKSVFGFM YYNTPFSLFP
PNAAISLTDD NSTSFAARPA AFGPKLASSG LSGQLWVGSG FGEDSLDTDG ELGCSDLPGW
GSSNTRASLK NSFKVGSTRL PSAKVKVPKK GGTLLDHDNR EAIAKGKAQA KSPKNDNTDN
YLTEEVAGTP SRRDSSVGSS GHADIQSIQE AAEIEGKIVL LKRGGCGFLE KVMWAQRRGA
IAVIVGDNQK GGPLIQMFAH GEDVDNVTVP SVFTARTTAQ LLSSLTQPGS FIEDTLDDNG
NAVLKVQQTP AATHKKQSLA KPRAATAAKG PNGSKAKRSV EGKRSKSAAE SGKGLGGGIF
SWGTTTRTVD SKSRPPRSGR LDWVLVDDFN DEKDRLISDT MGKAKRPKPR TDDFVIGVHD
WRDRDLVGTG EQKNTVEKNP AKNAGSGKSK DGDASSDSEP KPAGSDSKHH GLMSKLFGSD
SSDGSKSAMP SVDEGEDSPT IPPPPDGSQP HEGLWVTITP TSSASPFFDT LLVLVISPLV
TLTVVYALLI LRARIRRRRW RAPKSVVDQL PVRTYHTVAL SSPSLSPRLP SPSSATPTTP
LLQHSPSRPR PRSRTTTGVM ESENLLSASA AVPAPQPPRA SRRTEFEKGA GGFSAEWRKY
MGRQVECVVC LEEYVDGVSR VMSLPCGHEF HADCITPWLT TRRRTCPICK GDVVRSLARG
KGNGPRYDAY REDSDDDDEE EEDEAEASGS GSADRQSDLE QGISSSEPRD APQRPDRDGG
WLGVLSHSFN GRTRPHPQSP SPEDRNR
//
