ID E9F7E2_METRA Unreviewed; 680 AA.
AC E9F7E2;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Spindle assembly checkpoint component MAD1 {ECO:0000256|ARBA:ARBA00022019};
GN ORFNames=MAA_08191 {ECO:0000313|EMBL:EFY96279.1};
OS Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium
OS anisopliae (strain ARSEF 23)).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=655844 {ECO:0000313|EMBL:EFY96279.1, ECO:0000313|Proteomes:UP000002498};
RN [1] {ECO:0000313|EMBL:EFY96279.1, ECO:0000313|Proteomes:UP000002498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA Wang C.;
RT "Genome sequencing and comparative transcriptomics of the model
RT entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL PLoS Genet. 7:E1001264-E1001264(2011).
RN [2] {ECO:0000313|EMBL:EFY96279.1, ECO:0000313|Proteomes:UP000002498}
RP GENOME REANNOTATION.
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- SIMILARITY: Belongs to the MAD1 family.
CC {ECO:0000256|ARBA:ARBA00008029}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFY96279.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ADNJ02000004; EFY96279.1; -; Genomic_DNA.
DR RefSeq; XP_007824380.1; XM_007826189.1.
DR AlphaFoldDB; E9F7E2; -.
DR GeneID; 19262477; -.
DR KEGG; maj:MAA_08191; -.
DR HOGENOM; CLU_010064_0_0_1; -.
DR OrthoDB; 2787310at2759; -.
DR Proteomes; UP000002498; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:InterPro.
DR Gene3D; 3.30.457.60; -; 1.
DR Gene3D; 6.10.250.90; -; 1.
DR InterPro; IPR008672; Mad1.
DR PANTHER; PTHR23168:SF0; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1; 1.
DR PANTHER; PTHR23168; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1; 1.
DR Pfam; PF05557; MAD; 1.
DR SUPFAM; SSF75704; Mitotic arrest deficient-like 1, Mad1; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT REGION 43..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 421..459
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 488..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..71
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 421..439
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 440..459
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..507
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 680 AA; 76950 MW; 0A4FC66AA49FED08 CRC64;
MAPPDADEYE KYRKEIEALK AEIGTLHYRM QTADQEKEIA LSQQSNKLEQ ARRREQEELQ
QRQMAEADKD KAAGLVESVK AEMDELRERS QSDYKALERK AREAQDEARL LQEQLDDLST
AKDDEARIAD RKMNDMQMQI TALQTSIEEL EQESQSREEN VQQAHSVVAE KDSQIARLEA
DVLRLKAQSG DAETMEIIKR ELSEQVQHIR ALEATNRDQL SELKHLRAVS KAVEVVEEEK
RSLQRKLESA ESLEAELAEA RLHRQRLEDE RLAWASYLKH SSEAGDEFES PEAMARALME
ERLTAASYVE QVGAMRAEVS ARENSIQLLQ GEVGQLKDQL ENAKASAGML STDKARQRID
RQRILAVKEA EYLRAQIKAL DDEDQTMQPE KYDETRVARI QELENLVEQY KAEVQNLHAE
LSSLEPATGT ATPQPLSGTK RSRPEDDDAQ EQLGQLTRKN RKLQEDITGL QTKVTMLEKD
LSTSKEQLSA AKERNSTRVL SLRSNPTSDH EAIKRSTLEA LKKENSDLLL QLRSKHPNPA
VAVIPTSVLG AMEREIAAAK AETASAQKSA RRLKEVWASK SQEFKEAIFS TLGWTVTFIP
NGKMRVESTF FPSQTDEHEN SIVFDGERGT MKVGGGPKSP FARRIGDQIG FWVREKGCIP
GFLAALTLEF YEEHTRASRG
//
