ID E9FDE1_METRA Unreviewed; 497 AA.
AC E9FDE1;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=Glycoside hydrolase family 5 protein {ECO:0000313|EMBL:EFY94255.1};
GN ORFNames=MAA_10290 {ECO:0000313|EMBL:EFY94255.1};
OS Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium
OS anisopliae (strain ARSEF 23)).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=655844 {ECO:0000313|EMBL:EFY94255.1, ECO:0000313|Proteomes:UP000002498};
RN [1] {ECO:0000313|EMBL:EFY94255.1, ECO:0000313|Proteomes:UP000002498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA Wang C.;
RT "Genome sequencing and comparative transcriptomics of the model
RT entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL PLoS Genet. 7:E1001264-E1001264(2011).
RN [2] {ECO:0000313|EMBL:EFY94255.1, ECO:0000313|Proteomes:UP000002498}
RP GENOME REANNOTATION.
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC {ECO:0000256|ARBA:ARBA00005641, ECO:0000256|RuleBase:RU361153}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFY94255.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ADNJ02000027; EFY94255.1; -; Genomic_DNA.
DR RefSeq; XP_007826479.1; XM_007828288.1.
DR AlphaFoldDB; E9FDE1; -.
DR GeneID; 19264576; -.
DR KEGG; maj:MAA_10290; -.
DR HOGENOM; CLU_027657_0_0_1; -.
DR OrthoDB; 4254at2759; -.
DR Proteomes; UP000002498; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:1901136; P:carbohydrate derivative catabolic process; IEA:UniProt.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProt.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProt.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR041036; GH5_C.
DR InterPro; IPR001547; Glyco_hydro_5.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR31308; -; 1.
DR PANTHER; PTHR31308:SF3; CELLULASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00150; Cellulase; 1.
DR Pfam; PF18564; Glyco_hydro_5_C; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361153};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361153};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..497
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003236068"
FT DOMAIN 86..387
FT /note="Glycoside hydrolase family 5"
FT /evidence="ECO:0000259|Pfam:PF00150"
FT DOMAIN 407..494
FT /note="Glycoside hydrolase family 5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18564"
SQ SEQUENCE 497 AA; 54620 MW; 910E6FD5234284DA CRC64;
MYTYVYAGVV ALSLLGGGLA QDGAGWYAAH PGMARVQRVN QDTHQIVDEF GRARFFHGTN
VVMKEPPWHR PAEWVPGVSS FGERDVRNMR DLGLNVVRLG HSWAGAEPVR GEYNETFLDI
MRAQTSLAEA HGIYVLVDVH QDVLARQLCG HGVPDWFVKK DWVPAWERYP FPLKLSPFSV
DKDGFPSPAS LCGSVDWALS YTSVAVSNAF GRLYNNFDGL GDAFAAYWRK LAAGYAATAN
VVGYNLLNEP WVGDSWADPS LLVPGVADHK ALEGLWNRAA TQIRAVDNDT LIWFEGATLD
ILSGFNNVPL GDGARSVHSY HYYKPPQLGS IADTLANRRR DNERLRTAGV LTELTFWMGD
DQQMRDLADA MEATDAAMVS WIGWAYENLY NGTTGRPYPE LAGHYARAYP AAVAGVPRSF
GFDEKSATFT LRFTADPAID APTEVILPPA TFPGGYSVRI SPEGSLLQHK PDERTLALFT
SPGVKNATDV SVTITRA
//
