ID E9FUC4_DAPPU Unreviewed; 474 AA.
AC E9FUC4;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Junctophilin-3 {ECO:0008006|Google:ProtNLM};
GN ORFNames=DAPPUDRAFT_41319 {ECO:0000313|EMBL:EFX88944.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX88944.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX88944.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004163}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004163}. Membrane
CC {ECO:0000256|ARBA:ARBA00004211}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004211}.
CC -!- SIMILARITY: Belongs to the junctophilin family.
CC {ECO:0000256|ARBA:ARBA00008599}.
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DR EMBL; GL732525; EFX88944.1; -; Genomic_DNA.
DR AlphaFoldDB; E9FUC4; -.
DR STRING; 6669.E9FUC4; -.
DR EnsemblMetazoa; EFX88944; EFX88944; DAPPUDRAFT_41319.
DR KEGG; dpx:DAPPUDRAFT_41319; -.
DR eggNOG; KOG0231; Eukaryota.
DR HOGENOM; CLU_008078_4_1_1; -.
DR InParanoid; E9FUC4; -.
DR OMA; IRWPLRT; -.
DR PhylomeDB; E9FUC4; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0030314; C:junctional membrane complex; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR Gene3D; 2.20.110.10; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 3.
DR InterPro; IPR017191; Junctophilin.
DR InterPro; IPR003409; MORN.
DR PANTHER; PTHR23085; GH28348P; 1.
DR PANTHER; PTHR23085:SF16; GH28348P; 1.
DR Pfam; PF02493; MORN; 8.
DR SMART; SM00698; MORN; 6.
DR SUPFAM; SSF82185; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 3.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000305}.
FT REGION 162..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..244
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 267..304
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 474 AA; 51577 MW; EE197E419E6EAC3E CRC64;
MSSSPQKPVQ GGRFDFDDGG MYCGGWEDGK AHGHGVCTGL KGQGEYSGSW NYGFEVSGVY
TWPGGSTYEG HWQNGKRHGL GVESRGRWIY RGEWTQGFKG RYGVRQSLTS TAKYDGTWAN
GLQDGYGSET YADGGTYQGQ WLRGLRHGYG VRTSAPFGMA SRFRPKSVRS SMTSLRSADV
VSGHHHHHGH HHGAAASSSA AGGGAGADPA ADRDKRLDDG RGGFVLKARS DEPPARRRSF
SERSSTIKKT LFQGLRLKKQ HSTGELEKRG TSASIRSTGS SASWMSTESS QSGMTAGSHH
TDSNASFIAE DEPLDASVTE TYMGEWKNDK RAGFGISERS DGLKYEGEWF NNKKYGYGVT
TLKDGTKEEG KYKNNVLITS QKKKHLFLIR SAKFRERIEA AVSAAQRASK IALQKADIAI
SRTSTARGKA ELADVAAVHA REDADFAVII AKQLAPDFQP SKENLSSPFT FSFC
//
