ID E9G6U6_DAPPU Unreviewed; 1563 AA.
AC E9G6U6;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Kinesin-like protein unc-104 {ECO:0008006|Google:ProtNLM};
GN ORFNames=DAPPUDRAFT_314338 {ECO:0000313|EMBL:EFX84806.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX84806.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX84806.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
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DR EMBL; GL732533; EFX84806.1; -; Genomic_DNA.
DR STRING; 6669.E9G6U6; -.
DR EnsemblMetazoa; EFX84806; EFX84806; DAPPUDRAFT_314338.
DR KEGG; dpx:DAPPUDRAFT_314338; -.
DR eggNOG; KOG3510; Eukaryota.
DR HOGENOM; CLU_245829_0_0_1; -.
DR InParanoid; E9G6U6; -.
DR OMA; CINIPSA; -.
DR PhylomeDB; E9G6U6; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR CDD; cd22713; FHA_PHLB1; 1.
DR CDD; cd00063; FN3; 1.
DR CDD; cd00096; Ig; 2.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR12156:SF5; KINESIN-LIKE PROTEIN UNC-104; 1.
DR PANTHER; PTHR12156; PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 2.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50835; IG_LIKE; 2.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..70
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 73..177
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1454..1556
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 366..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 622..649
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 677..723
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 791..889
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 909..933
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1133..1152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1314..1359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1403..1422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 731..786
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 968..1066
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 366..381
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 635..649
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 700..723
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 794..813
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 825..889
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1314..1332
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1406..1421
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1563 AA; 174681 MW; EF20151BAAC14F97 CRC64;
MATGRPMPTV TWKYQGRVLS AEESIVDVNQ KVSSVHRIVG ARKVDAGAYI CEADNGVDIP
AVATFVVEIS HAPEIVVEHS WVHTGLGSLT ELACTVYAHP AAQVTWFRSV ESVGNNEGNT
GRKHLQVIPS NRVGTLVMSN GLKHVLRFKS VQDSDLGIYT CKAENLHGQA EAAIEMSGKA
MAAVLWISPP RGASKLIDSE QQEDDESKAG RRIGYRLTWD AVSLSPIYEY RLWLRPRGQP
EISWVNLIIP SNSSTGSSSS PSLHSHGYEL SDLATGIVYQ VSVQSRNRFG WSAESNTVNL
SGGEDPEVTD YDNSDITSSS SANIIPVEQS SGGARDDKMM ATAAVKRAWL NANHHHHQQL
VNVSSLDGDS RPYWQQQPQQ QPPQQWTPPP DPHYRPVNAA YSRHHSPSPG VEVCEQGHNA
LKVRTADCGP HLVSLGSGRL STNITLIHLP EGRILMGCGG SYVQRQPDVH VQGTGVEPIH
CYIENINGTV SLYPLGEMTS VDGLPVATPI RLTQGSMICV GRSNYFRFNH PEEAERMKTI
LPNARISSVP MNFANASSIS GITSAPSAAS PEPPGMDNPE YFHMPGLNGH HHPHSNGNSA
FQPVRSSSPQ YIGEYLHPRM LSHFDHDDDD DYEVSVPTSP QQQSRWHSAS PKVFLPNSST
VSLPASAVLG LRGRSATPTA IPTCNPTSAE AHSAHKRSHS VGASHSLNLQ QQQQQHQPQQ
PKPILRQERS LEALAACEEQ LEERRRKAQE DRVKEQEQER EERARLDEIL QMCAEYQRQI
DDEQRHSRDA FTLSDTRPDS PSYSKQLSHS AASGKPPPSP GHSLHPNRIK TNGSLPRNET
RRSVQSPNGT TSAGRNLNTS EDELSGIFTF DPTPNSVPAS PSLSNHQQQT VAADLAVSCK
SPYENVCMPQ SPRTRIRTTV GKNKEDSPES LSTNQHTYQL ITSGVAAEVA KREAGRLEKE
CQQIMCIISA LKNHVTDVEH QIDEAIREAE MERALLQGEL TAQLEKILQD EKWIEQLEQK
DQKLAAELDE FRFEEGAKIQ TSKSKMEAIE LELNQLEEEC DAFSGSTDEE TALLEKIKFQ
HELLDTERKS FEDLEFRLME GVAHREAERE ELHKEMAGVE LRLLQRRQQL REVEQQQRQA
SDSARSEAQE LANKRKELFQ QIEEEKSKLV ALQSKLEQLF RAGLAGGHYD NGAEASSDTE
ESVTDIEQRL QELRQMGHSQ EDLDRIERIA SQNRALNNTD DQSRKATATL MEIERNRQLI
LVQQGAQVLE YERKKVAELK RRVQDQVRAQ WEERRSMEQQ QQPVDREVNC HSLNSVGSSE
ESRSSLTGSD APTESDDVPA KPGGPDRGSN GSTASAPSAS ITSILEVKVR QHDFHQPLED
CRPLSEASSF GGEELPGEVR LRDKQRAQQV QQQQQQQRPL TRYLPVRGDG FDLRQHVETA
GHQVELCPHV TLTSTSARGY LHKMGSRFKT WNKRWFVFDR TQRTFLYFTD KSETRKRSGA
YFQAIEEVYV DHLQSVRSPN PKLTFCVKTR ERTYHLMAPS AEAMRIWVDV IFTGAEGYQQ
FHV
//
