ID E9H1P6_DAPPU Unreviewed; 592 AA.
AC E9H1P6;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Solute carrier family 13 member 5 {ECO:0008006|Google:ProtNLM};
GN ORFNames=DAPPUDRAFT_226776 {ECO:0000313|EMBL:EFX74214.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX74214.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX74214.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family.
CC NADC subfamily. {ECO:0000256|ARBA:ARBA00006772}.
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DR EMBL; GL732584; EFX74214.1; -; Genomic_DNA.
DR AlphaFoldDB; E9H1P6; -.
DR STRING; 6669.E9H1P6; -.
DR EnsemblMetazoa; EFX74214; EFX74214; DAPPUDRAFT_226776.
DR KEGG; dpx:DAPPUDRAFT_226776; -.
DR eggNOG; KOG1281; Eukaryota.
DR HOGENOM; CLU_005170_9_1_1; -.
DR InParanoid; E9H1P6; -.
DR OMA; IWWMTEA; -.
DR PhylomeDB; E9H1P6; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015137; F:citrate transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015141; F:succinate transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015746; P:citrate transport; IBA:GO_Central.
DR CDD; cd01115; SLC13_permease; 1.
DR InterPro; IPR031312; Na/sul_symport_CS.
DR InterPro; IPR001898; SLC13A/DASS.
DR PANTHER; PTHR10283:SF82; PROTEIN I'M NOT DEAD YET-RELATED; 1.
DR PANTHER; PTHR10283; SOLUTE CARRIER FAMILY 13 MEMBER; 1.
DR Pfam; PF00939; Na_sulph_symp; 1.
DR PROSITE; PS01271; NA_SULFATE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 439..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..519
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 531..553
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 193..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..207
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 592 AA; 65217 MW; 9B3829A9115D043E CRC64;
MLKFLRNHIF PYWRSIIVVT VPLLLLPLPI IAGTKEASCG YTILIMAIYW MTEALPLPIT
SLIPVVAFPL FGILDTGDVC MAYMKETNMM FIGGLILALG IEFCNLHKRV ALAVLLLVGA
KPRWLMVGFM GTTAFLSMWI SNTATTAMMV PIVEAVVAEL YKDEDDKSVG SSHITVAISN
DSIQELVPDS LSIKDNSEKN SSTSSQAAKD TEKERRRKVR VGVMMCIAYA SNIGGTGSLI
GSSPQLALKG IVQETFGSTE LNFASWMAFN IPGVIINLFF AWLWIQFLFI GFKGQSSDQD
REKEVKKMIR RKFRDLGPMT FHEGAVLLLF IVCVMLWFFR DPGFVPGWAH FIEDAHVDDA
TAVMIIVLFL FSIPAKPSFW CLRPKGETGP EKPSPALLDW KYVQDRLPWG IVLLLGGGFA
LSDATQASGL SDWIGQQLIV LKVLPPFVIM LIICIITATI TEIASNTATA NILLPILADT
AVSIGVNPLY LMVPATVTCS YAFMLPVATP PNAIVFSAAK MNPVEMMKSG WFMNLVCVIV
ICVLMETWGS VIFNSNEFPA WANTTLTDKN ENQCNITELL STTMSDVSIW GN
//
