ID E9HCL2_DAPPU Unreviewed; 904 AA.
AC E9HCL2;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 61.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=DAPPUDRAFT_328037 {ECO:0000313|EMBL:EFX70495.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX70495.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX70495.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
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DR EMBL; GL732620; EFX70495.1; -; Genomic_DNA.
DR AlphaFoldDB; E9HCL2; -.
DR STRING; 6669.E9HCL2; -.
DR EnsemblMetazoa; EFX70495; EFX70495; DAPPUDRAFT_328037.
DR KEGG; dpx:DAPPUDRAFT_328037; -.
DR eggNOG; KOG1178; Eukaryota.
DR eggNOG; KOG4649; Eukaryota.
DR HOGENOM; CLU_010423_0_0_1; -.
DR InParanoid; E9HCL2; -.
DR OMA; NGNVICC; -.
DR PhylomeDB; E9HCL2; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0043041; P:amino acid activation for nonribosomal peptide biosynthetic process; IBA:GO_Central.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR InterPro; IPR002372; PQQ_repeat.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR44394; BETA-ALANINE-ACTIVATING ENZYME; 1.
DR PANTHER; PTHR44394:SF1; BETA-ALANINE-ACTIVATING ENZYME; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13360; PQQ_2; 2.
DR Pfam; PF13570; PQQ_3; 1.
DR SMART; SM00564; PQQ; 5.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305}.
FT DOMAIN 498..573
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 904 AA; 100482 MW; 5AFEE47CC5E0210C CRC64;
MTKTLLDCVF PIRNPQSPAV TYHDGECSIT LLYGDLSDDV QQISKALLPI CYENCVVVFA
IQQLHHLVPS LILGVLKSKA SFMYLDPDFP LLKQEEVVKR SKASVIISDS AKAFSGWKLT
TTVRVFGANE LHIFQECLPS KLVNFPLPEE WNIAYLIHTS GSTGTPKVVR VPHTCLLPNI
LDLRKIFNIQ QTDVIFIASP FTFDPSIVDL FLTFSTGARM VLVKPSIKAM PSKLAEIIRK
EGVTFLQATP SFLLQFGPEL SKTHLLYPSS PLRIIVLGGE AFPALKTLSE FSSPGHSTVF
YNIYGITEVS CWATLSKIES NEIQVDLGHA LGETDLRVIN EDEEEIHRDQ GGEGYLWLGG
RRICLLDDET PDSIEKPVFR PTGDRVEFLN GKLYYRGRKD ETVKRMGKRL NLHSVEILAL
SSGLVQQCCA LLDSNRLLVL VCNGISVIDH LLQFFQENAA AVEQPDVIRI LDSLPMSKHG
KIDRKKLLQI IQTTPKHDGK LNWETILANE WRNATGQTAT DESNFILSGG NSLSALRLVN
QIQEETSRSL PLLTDILLNQ NWKETVDYIR KESLNGPISS LQIQVAHPKS KVEIFQRSQP
SSKVTDVISK ASTLELKQIW KFNLKKCIDA SPLVIRRKEG DAVFIGSHSH RFSAVKLDSG
QEIWTTELPE RIESSASCDM NGVNIFVGCY DGNLYCLDAL TGRICWHYST GDAIKSSPVC
TGPSVVFGSH DRTLYSLSVA RGELLWRKTI SEGSLFASVA WDGSNRILSA ALDGTCSALS
VTSGELLWTI KLSTPIFSSP VWFSKSERCL LASVDGFINC CSADTGDIVW RYQAAGPIFS
TPTVADKRII FGSHDHFLYC LDEESAQTRL DGEVFSSPVM VDQLVVVGCR DNHLYCFELV
NDCM
//
