ID   E9RUT9_9FIRM            Unreviewed;       706 AA.
AC   E9RUT9;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   24-JAN-2024, entry version 38.
DE   SubName: Full=Anaerobic ribonucleoside-triphosphate reductase {ECO:0000313|EMBL:EGC75060.1};
GN   ORFNames=HMPREF0490_01224 {ECO:0000313|EMBL:EGC75060.1};
OS   Lachnospiraceae bacterium 6_1_37FAA.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=658656 {ECO:0000313|EMBL:EGC75060.1, ECO:0000313|Proteomes:UP000006471};
RN   [1] {ECO:0000313|EMBL:EGC75060.1, ECO:0000313|Proteomes:UP000006471}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=6_1_37FAA {ECO:0000313|EMBL:EGC75060.1,
RC   ECO:0000313|Proteomes:UP000006471};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA   Ambrose C., Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA   Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.,
RA   Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA   Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA   Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., White J.,
RA   Yandava C., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 6_1_37FAA.";
RL   Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGC75060.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ADCR01000011; EGC75060.1; -; Genomic_DNA.
DR   AlphaFoldDB; E9RUT9; -.
DR   STRING; 658656.HMPREF0490_01224; -.
DR   HOGENOM; CLU_002707_2_0_9; -.
DR   Proteomes; UP000006471; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008998; F:ribonucleoside-triphosphate reductase activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   Gene3D; 3.20.70.20; -; 1.
DR   InterPro; IPR005144; ATP-cone_dom.
DR   InterPro; IPR012833; NrdD.
DR   NCBIfam; TIGR02487; NrdD; 1.
DR   PANTHER; PTHR21075; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR   PANTHER; PTHR21075:SF0; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR   Pfam; PF03477; ATP-cone; 1.
DR   Pfam; PF13597; NRDD; 1.
DR   SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR   PROSITE; PS51161; ATP_CONE; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00492};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00492}.
FT   DOMAIN          2..93
FT                   /note="ATP-cone"
FT                   /evidence="ECO:0000259|PROSITE:PS51161"
SQ   SEQUENCE   706 AA;  80747 MW;  F0A23D487A9FE7B8 CRC64;
     MVKVIKKDGT SEEFNVQKVV VAVNKSAYRA LIQFTDAELE FICKFVEEKV RDMGVEEVRI
     AEMHNIVEGA LEKVNPLVAK SYRDYRNYKQ DFVQMLDEVY KKSQSIMYIG DKENSNTDSA
     LVSTKRSLIF NELNKELYKK FFLTTEEIQA CRDGYIYIHD MSARRDTMNC CLFDVKNVLS
     GGFEMGNLWY NEPKTLDTAF DVIGDIVLSA ASQQYGGFTV PSVDDILEPF AEKSFHNHVE
     KYLGLGIERE KAEEVAWKDL EKEMEQGFQG WEYKFNSVSS SRGDYPFITV TAGTGRSRFA
     KLVTITMLKV RMNGQGKEGH KKPVLFPKIV FLYDENLHGP GKELEDVFEA GIECSRKTMY
     PDWLSLTGKG YIASMYKQYG KIISPMGCRA FLSPWYEKGG MYPKDETDTP VFVGRFNIGA
     VSLHLPMIYA KAKQENKDFY EVLDYYLNLI RKLHIRTYEY LGEMKASTNP LAYCEGGFYG
     GNLGLHDKIK PLLKSATASF GITAFNELQQ LHNKKSLVED GAFALEVLEY INKRVNEFKE
     EDGHLYAIYA TPAENLCGLQ VKQFRKKYGI VENVSDREYV SNGFHCHVTE DITPIEKQDL
     EYRFWELSNG GKIQYVKYPI NYNKEAIKAL VRRAMDMGLY EGVNLSLAYC DDCGHEELAM
     DVCPVCGSKN LTKIDRMNGY LSYSRVKGDT RLNDAKMAEI AERKSM
//