ID E9RZ46_9FIRM Unreviewed; 557 AA.
AC E9RZ46;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE RecName: Full=HAMP domain-containing protein {ECO:0000259|PROSITE:PS50885};
GN ORFNames=HMPREF0490_02734 {ECO:0000313|EMBL:EGC73504.1};
OS Lachnospiraceae bacterium 6_1_37FAA.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=658656 {ECO:0000313|EMBL:EGC73504.1, ECO:0000313|Proteomes:UP000006471};
RN [1] {ECO:0000313|EMBL:EGC73504.1, ECO:0000313|Proteomes:UP000006471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=6_1_37FAA {ECO:0000313|EMBL:EGC73504.1,
RC ECO:0000313|Proteomes:UP000006471};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Ambrose C., Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., White J.,
RA Yandava C., Nusbaum C., Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 6_1_37FAA.";
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGC73504.1}.
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DR EMBL; ADCR01000026; EGC73504.1; -; Genomic_DNA.
DR AlphaFoldDB; E9RZ46; -.
DR STRING; 658656.HMPREF0490_02734; -.
DR HOGENOM; CLU_020473_6_2_9; -.
DR Proteomes; UP000006471; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 250..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 275..327
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
SQ SEQUENCE 557 AA; 64172 MW; AEB917E278B72E36 CRC64;
MKQRQQTLDA IQSNNDSYIA RLDENLQQIY TANLHIIEQN FLRDLAVIYP YLSTYDKSVR
VNLLREQLSS LCASSPLLES AHAYLFNYNL MYNSDNYPIG SYCTLTEEET RFYQELSKTH
GLVEYYESPL EKRKTLSVFM APFSSSPAFA VNFILSENAL KSYLESNSSY SDEFYLFEIE
NGFSLSNLPS DLRKEASNFL KQNAHTSAPS YQKVELHGKS YTAFLSRMES SSGIYVRLIS
DTSLLPSIRY SYGLLFLFFF LIICASILFF IGIYRMVHKP LSKLTDAFDE VEHGNFQVQI
IQTGNDDFAY LYHAFNNMAL KLSRLIERDY NQKLLLQKAE MKQLQAQINP HFLYNSFFML
QRMIRFEPEE ASMVANALAS CFRYITKNSM DHVTLAEEYA HMKNYVYIQG LRFAGRIQIE
LEELPDCFSS LSVPKLILQP ILENAFQYGL KNKICDGLIR VRFLSKEHAL FMIIEDNGEE
LSDELLTTLQ KKLQDSAHSS AGVEMSGILN IQRRLHIFSN DRDTLEISRS LLGGLCATIT
LHMESDDYSG SFRNNNT
//
