ID F0EKB7_ENTCA Unreviewed; 310 AA.
AC F0EKB7;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU {ECO:0000256|HAMAP-Rule:MF_01140};
DE EC=2.7.8.- {ECO:0000256|HAMAP-Rule:MF_01140};
GN Name=lytR {ECO:0000313|EMBL:EGC69575.1};
GN Synonyms=tagU {ECO:0000256|HAMAP-Rule:MF_01140};
GN ORFNames=HMPREF9087_1859 {ECO:0000313|EMBL:EGC69575.1};
OS Enterococcus casseliflavus ATCC 12755.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=888066 {ECO:0000313|EMBL:EGC69575.1, ECO:0000313|Proteomes:UP000004835};
RN [1] {ECO:0000313|EMBL:EGC69575.1, ECO:0000313|Proteomes:UP000004835}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12755 {ECO:0000313|EMBL:EGC69575.1,
RC ECO:0000313|Proteomes:UP000004835};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May catalyze the final step in cell wall teichoic acid
CC biosynthesis, the transfer of the anionic cell wall polymers (APs) from
CC their lipid-linked precursor to the cell wall peptidoglycan (PG).
CC {ECO:0000256|HAMAP-Rule:MF_01140}.
CC -!- PATHWAY: Cell wall biogenesis. {ECO:0000256|HAMAP-Rule:MF_01140}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_01140};
CC Single-pass type II membrane protein {ECO:0000256|HAMAP-Rule:MF_01140}.
CC -!- SIMILARITY: Belongs to the LytR/CpsA/Psr (LCP) family.
CC {ECO:0000256|ARBA:ARBA00006068, ECO:0000256|HAMAP-Rule:MF_01140}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGC69575.1}.
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DR EMBL; AEWT01000013; EGC69575.1; -; Genomic_DNA.
DR AlphaFoldDB; F0EKB7; -.
DR HOGENOM; CLU_016455_2_2_9; -.
DR Proteomes; UP000004835; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:UniProtKB-UniRule.
DR GO; GO:0070726; P:cell wall assembly; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.630.190; LCP protein; 1.
DR HAMAP; MF_01140; TagU_transferase; 1.
DR InterPro; IPR004474; LytR_CpsA_psr.
DR InterPro; IPR023734; TagU.
DR NCBIfam; TIGR00350; lytR_cpsA_psr; 1.
DR PANTHER; PTHR33392; POLYISOPRENYL-TEICHOIC ACID--PEPTIDOGLYCAN TEICHOIC ACID TRANSFERASE TAGU; 1.
DR PANTHER; PTHR33392:SF6; POLYISOPRENYL-TEICHOIC ACID--PEPTIDOGLYCAN TEICHOIC ACID TRANSFERASE TAGU; 1.
DR Pfam; PF03816; LytR_cpsA_psr; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_01140};
KW Cell wall biogenesis/degradation {ECO:0000256|HAMAP-Rule:MF_01140};
KW Membrane {ECO:0000256|HAMAP-Rule:MF_01140, ECO:0000256|SAM:Phobius};
KW Signal-anchor {ECO:0000256|HAMAP-Rule:MF_01140};
KW Transferase {ECO:0000256|HAMAP-Rule:MF_01140};
KW Transmembrane {ECO:0000256|HAMAP-Rule:MF_01140, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_01140,
KW ECO:0000256|SAM:Phobius}.
FT TOPO_DOM 1..6
FT /note="Cytoplasmic"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01140"
FT TRANSMEM 7..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TOPO_DOM 28..310
FT /note="Extracellular"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01140"
FT DOMAIN 84..227
FT /note="Cell envelope-related transcriptional attenuator"
FT /evidence="ECO:0000259|Pfam:PF03816"
SQ SEQUENCE 310 AA; 34738 MW; 768BB0C937D45451 CRC64;
MSKGKKIFLI IFSIVAVLVI GMIGVAAKLY FDVSNSIQET YQSVERDRED RLRENDVDLS
QKDSFSVLLM GIDTGDLGRV EQGRSDTMMV ATISPQDNQT TVVSIGRDSY VDIVGHGTTD
KINHAYAFGG PAMAMNTVEK FLDIPIDHYV SINMAGLKEL VDAVGGIEVD NEITFSQDGF
DFAIGRTSLN GEQALAYSRM RYEDPNGDYG RQERQRKIVE GIVKKVLSLD GITQYQTILN
AVEQNMKTDM SFDDMRTLAF NYRSAFQTIK QDQLQGEGFM QDGISYQRVS DEELARVQKE
LKAQLNLENE
//
