ID F0EQG8_HAEPA Unreviewed; 619 AA.
AC F0EQG8;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Selenocysteine-specific translation elongation factor {ECO:0000313|EMBL:EGC73225.1};
GN Name=selB {ECO:0000313|EMBL:EGC73225.1};
GN ORFNames=HMPREF9417_0112 {ECO:0000313|EMBL:EGC73225.1};
OS Haemophilus parainfluenzae ATCC 33392.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=888828 {ECO:0000313|EMBL:EGC73225.1, ECO:0000313|Proteomes:UP000005577};
RN [1] {ECO:0000313|EMBL:EGC73225.1, ECO:0000313|Proteomes:UP000005577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33392 {ECO:0000313|EMBL:EGC73225.1,
RC ECO:0000313|Proteomes:UP000005577};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGC73225.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEWU01000004; EGC73225.1; -; Genomic_DNA.
DR RefSeq; WP_005694814.1; NZ_UGHU01000001.1.
DR AlphaFoldDB; F0EQG8; -.
DR GeneID; 67392540; -.
DR HOGENOM; CLU_023030_2_0_6; -.
DR Proteomes; UP000005577; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR048931; SelB_WH_3rd.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF21214; bact_SelB_WH_2nd; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF09106; SelB-wing_2; 1.
DR Pfam; PF09107; SelB-wing_3; 1.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:EGC73225.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000313|EMBL:EGC73225.1}.
FT DOMAIN 1..166
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 619 AA; 69679 MW; 8D6F16FD425442D8 CRC64;
MIIVTSGHVD HGKTALLKAL TGTNTAHLPE EKKRGMTIDL GYAYLPLKEK VLGFIDVPGH
EKFLANMLAG LGGVHYAMLI VAADEGIAAQ TKEHLAILRQ LQFTEIMVVI TKADRATDEQ
IEALKTQIQT AYPFLAESHY FITSAQTGLG IDSLRDYLAN LPELAEIDKP FRYAIDRVFS
VKGAGTVVTG TAFAGTVAID DELFLSTGQK VRVKNIHAQN KPSEKGLAGQ RLALNLNVDL
DRIPMQRGDW LLASEPLEPT DRITIEITPE VNLKDSQPVH IYHAASRTTG KLTLLESKNA
MKNDRTLAEV ILEQPLFLAF GDKLILRSGD AKALIGGAKV LEIHSPKRYK RTEARLAFLA
KLNQVQTATQ RIGLTLQKEA ISAQALMWSE QLTENQLAEA LAENGDIRFQ NWCFNRDYQR
EKTQQILTAL ATYHEQHNDQ LGLSKARLYR IATLNQPENL IYHFIEEMLD EGQLQQTRGW
LHLPSHKIQF SAEEQSLWQA VLAEFEKAHG QAIWVRDMAT ALAQDESVMR NFMYKAGKLG
YLTPIVKDRF FLTESIYAYA RLIKEIAGEE GKVAVNELRD KLNFGRKLTV QLMEYFDRTG
FLRRKGNDHI LRDKDTFDL
//
