ID F0F3N8_9BACT Unreviewed; 660 AA.
AC F0F3N8;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE SubName: Full=Succinate dehydrogenase or fumarate reductase, flavoprotein subunit {ECO:0000313|EMBL:EGC21454.1};
DE EC=1.3.99.1 {ECO:0000313|EMBL:EGC21454.1};
GN Name=sdhA {ECO:0000313|EMBL:EGC21454.1};
GN ORFNames=HMPREF9141_0204 {ECO:0000313|EMBL:EGC21454.1};
OS Prevotella multiformis DSM 16608.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=888743 {ECO:0000313|EMBL:EGC21454.1, ECO:0000313|Proteomes:UP000005697};
RN [1] {ECO:0000313|EMBL:EGC21454.1, ECO:0000313|Proteomes:UP000005697}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16608 {ECO:0000313|EMBL:EGC21454.1,
RC ECO:0000313|Proteomes:UP000005697};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGC21454.1}.
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DR EMBL; AEWX01000001; EGC21454.1; -; Genomic_DNA.
DR RefSeq; WP_007367745.1; NZ_GL872283.1.
DR AlphaFoldDB; F0F3N8; -.
DR STRING; 888743.HMPREF9141_0204; -.
DR eggNOG; COG1053; Bacteria.
DR HOGENOM; CLU_014312_7_0_10; -.
DR OrthoDB; 9806724at2; -.
DR Proteomes; UP000005697; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR011280; Succ_DH/Fum_Rdt_flav_su.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR NCBIfam; TIGR01811; sdhA_Bsu; 1.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF53; SUCCINATE DEHYDROGENASE FLAVOPROTEIN SUBUNIT; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EGC21454.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005697}.
FT DOMAIN 37..461
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 523..658
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT ACT_SITE 339
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR630664-50"
SQ SEQUENCE 660 AA; 73556 MW; 2F4A953EDEC1C9BE CRC64;
MTKTLNSRIP EGPVAEKWTN YKAHQRLVNP KNKLKLDVIV VGTGLAGASA AASLGEMGFN
VLNFCIQDSP RRAHSIAAQG GINAAKNYQN DGDSVYRLFY DTVKGGDYRA REANVYRLAE
VSNDIIDQCV AQGVPFAREY GGMLANRSFG GAQVSRTFYA KGQTGQQLLL GAYSSLSAQI
QAGKVKLYTR YEMEDVVIVD GHARGIIAKN LITGKLERFS ANAVVIATGG YGNTYFLSTN
AMGCNCTAAI QCYRKGAYMA NPSYVQIHPT CIPVHGDKQS KLTLMSESLR NDGRIWVPKK
LEDAKALQAG TKKGSDIPEE DRDYYLERRY PAFGNLVPRD VASRAAKERC DKGFGVNNTG
LAVFLDFSES INRLGIDTIL QRYGNLFDMY EEITDVNPGE VANEINGVKY YNPMMIFPAI
HYTMGGIWVD YELMTTVPGL FSIGECNFSD HGANRLGASA LMQGLADGYF VLPYTIQNYL
ADQALWGRIP TDRPEFDEAE KAVDAEIDRL MGIHGKRSVD SIHKELGHIM WEHVGMGRTK
EGLEEGLKQL KALREEFNTN LFIPGKKEGL NVELDKAIHL RDFILMGELV AYDALHREES
CGGHFREEHQ TEEGEAKRDD EHFFYVGCWE YQGDDTKAPE LIKEPLEYEA IKVQTRNYKN
//
