ID F0FGP9_STRSA Unreviewed; 1405 AA.
AC F0FGP9;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE SubName: Full=LPXTG-motif cell wall anchor domain protein {ECO:0000313|EMBL:EGC21906.1};
DE EC=3.2.1.80 {ECO:0000313|EMBL:EGC21906.1};
GN ORFNames=HMPREF9388_1882 {ECO:0000313|EMBL:EGC21906.1};
OS Streptococcus sanguinis SK353.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=888815 {ECO:0000313|EMBL:EGC21906.1, ECO:0000313|Proteomes:UP000004185};
RN [1] {ECO:0000313|EMBL:EGC21906.1, ECO:0000313|Proteomes:UP000004185}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK353 {ECO:0000313|EMBL:EGC21906.1,
RC ECO:0000313|Proteomes:UP000004185};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 32 family.
CC {ECO:0000256|ARBA:ARBA00009902}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGC21906.1}.
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DR EMBL; AEWY01000011; EGC21906.1; -; Genomic_DNA.
DR RefSeq; WP_002898976.1; NZ_GL872307.1.
DR PATRIC; fig|888815.3.peg.1852; -.
DR HOGENOM; CLU_005855_0_0_9; -.
DR Proteomes; UP000004185; Unassembled WGS sequence.
DR GO; GO:0051669; F:fructan beta-fructosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd18622; GH32_Inu-like; 1.
DR Gene3D; 2.60.40.1080; -; 1.
DR Gene3D; 1.20.1270.90; AF1782-like; 1.
DR Gene3D; 2.20.230.10; Resuscitation-promoting factor rpfb; 1.
DR InterPro; IPR003343; Big_2.
DR InterPro; IPR025883; Cadherin-like_b_sandwich.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR011098; G5_dom.
DR InterPro; IPR001362; Glyco_hydro_32.
DR InterPro; IPR018053; Glyco_hydro_32_AS.
DR InterPro; IPR013189; Glyco_hydro_32_C.
DR InterPro; IPR013148; Glyco_hydro_32_N.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR InterPro; IPR008964; Invasin/intimin_cell_adhesion.
DR InterPro; IPR022263; KxYKxGKxW.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR019931; LPXTG_anchor.
DR NCBIfam; TIGR03715; KxYKxGKxW; 1.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR PANTHER; PTHR42800; EXOINULINASE INUD (AFU_ORTHOLOGUE AFUA_5G00480); 1.
DR PANTHER; PTHR42800:SF1; EXOINULINASE INUD (AFU_ORTHOLOGUE AFUA_5G00480); 1.
DR Pfam; PF02368; Big_2; 1.
DR Pfam; PF12733; Cadherin-like; 1.
DR Pfam; PF07501; G5; 1.
DR Pfam; PF08244; Glyco_hydro_32C; 1.
DR Pfam; PF00251; Glyco_hydro_32N; 1.
DR Pfam; PF00746; Gram_pos_anchor; 1.
DR Pfam; PF02210; Laminin_G_2; 1.
DR SMART; SM00635; BID_2; 1.
DR SMART; SM01208; G5; 1.
DR SMART; SM00640; Glyco_32; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 2.
DR SUPFAM; SSF49373; Invasin/intimin cell-adhesion fragments; 1.
DR PROSITE; PS51109; G5; 1.
DR PROSITE; PS00609; GLYCOSYL_HYDROL_F32; 1.
DR PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
PE 3: Inferred from homology;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:EGC21906.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EGC21906.1};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Secreted {ECO:0000256|ARBA:ARBA00022512};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 1259..1334
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT DOMAIN 1373..1405
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|PROSITE:PS50847"
FT REGION 85..134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1204..1241
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 85..103
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..133
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1405 AA; 156304 MW; 1B14552D9830A1CA CRC64;
MKNHQEKVCK NWFMRKSGKR WVFGCALLAF GAFLLDGGGV VYADEGKANP APAQVLQTDS
SAVSEPESGQ TAALTMNADK VENSVAGETA TTEAGSQDAA VESANQKADK EDQVTANARE
TKQEEDEQTA AKEVVSEKLP AAETVDKQSG FNTNLAEAKG DKNGVWEVRE QGLYSDARGK
GDSFLYSQSQ GKDFVYSTDV TFLSKEGAAA LIFRGNNNPD DKSSYAVNID GGSNNVKFWR
WQGGRDYQFI NEKHIEPTDD NKYRLKVVSI GSWVSYYVND ILVASSGDYT LQRDDKGQNT
YLSEGYFGLL NWNSELLFQN TFYKEITPQS NPELEDIRVT SSVGKVEQKG QFTAPITIQY
VKHDAETVDL TAVAKNPAAK VSVTDAAGRV YSDLKNVPLA VGANYLTVTS TVTDADGQEV
SLTYRLNVHR RQADEIYYNE LYRGQYHYSV KDGWANDPNG LVYYKGVYHF FYQFYDDTKW
GPMHWGHATS KDLIHWEEQP IAFYPDANGA MFSGSIVADT TNSSGLFDND QGGLIALITA
DGNGQRIKLA YSKDEGRTWT KLDQIAADWT DDPLQSQDFR DPKVFRWEGK WFMVVAGGPL
RIYSSDNLRN WKVESTYADL HTECPDLYPL LADDGSLKWV LSRGGRSYKV GDFRQVAGKW
TFVPDAEFAQ ADQVMNFGKD SYAAMTYYVQ DFGSKANPTL PDIIESNWMN TWEDYCNLVA
DTVGQKFNGT FNLNLKLGLI KQDRSYRLTQ TPITAYQSLR QEDKAVLYKD VEVSEKNELL
KDFSGDQYEI VSTFRPSETT KKVGFNLRVG DGEVTRVTYD LEKEILSIDR SQSGILLSNK
FAQVDSQSVK RNADGSIDLH LYVDRSSLEV FAKGYTVAGA NQIFPAPNSL AARVFVEGGA
AKADIALYPL KGIWKDKQVV TKPLELVQAS PVTNNIYVGD TLDLKAYVMP ATVSQAVSWS
VDQPDLVSVT EDGNKLRVTA LQRGVVKVTA TSKENPNLSK VFTINISRND FKTNVPDLKA
VSGKWYVDGE SLYNQNTSAN DYYMGGQKIP FPEYNLDVDL KYQKGLINIF YASENVDPRN
AYSIQFGDND KIRLYRFMGE TIAESSMNGK HLNDGQFHHV KLVKTKNGVS VSVDGVEYLN
HQFDTVEPYY NDAYVGLGLW DGDLEARNFF VTNLHEPAVN KASLQKVVDS TASLDPSLYT
DETVQAYQSA LARAQSLLAD EKAEQADLDR AEQDLKTALA ALAVKPSHQV TPEEGIKDLV
EEKPFLEIVM EEIAYQTREQ ENPELERGQR RILVAGQKGQ KRVFVEVLNG QRTVLGQEVL
SLAVDELVEV GSKVVAESAK QPLTRTQPHA LNQGKEEKVI LSPRLQPAPD SALPKTGTQE
DKFLTLAGLA FLGMGLLAGR KKQED
//
