ID F0FQI0_STRSA Unreviewed; 606 AA.
AC F0FQI0;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Glycosyl hydrolase family 35 {ECO:0000313|EMBL:EGC27685.1};
DE EC=3.2.1.23 {ECO:0000313|EMBL:EGC27685.1};
GN Name=bgaC {ECO:0000313|EMBL:EGC27685.1};
GN ORFNames=HMPREF9392_0206 {ECO:0000313|EMBL:EGC27685.1};
OS Streptococcus sanguinis SK678.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=888819 {ECO:0000313|EMBL:EGC27685.1, ECO:0000313|Proteomes:UP000003133};
RN [1] {ECO:0000313|EMBL:EGC27685.1, ECO:0000313|Proteomes:UP000003133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK678 {ECO:0000313|EMBL:EGC27685.1,
RC ECO:0000313|Proteomes:UP000003133};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGC27685.1}.
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DR EMBL; AEXA01000004; EGC27685.1; -; Genomic_DNA.
DR AlphaFoldDB; F0FQI0; -.
DR PATRIC; fig|888819.3.peg.200; -.
DR HOGENOM; CLU_007853_7_2_9; -.
DR Proteomes; UP000003133; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR026283; B-gal_1-like.
DR InterPro; IPR048912; BetaGal1-like_ABD1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF21317; BetaGal_ABD_1; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PIRSF; PIRSF006336; B-gal; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:EGC27685.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EGC27685.1}.
FT DOMAIN 20..339
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 384..499
FT /note="Beta-galactosidase 1-like first all-beta"
FT /evidence="ECO:0000259|Pfam:PF21317"
FT DOMAIN 517..575
FT /note="Beta-galactosidase galactose-binding"
FT /evidence="ECO:0000259|Pfam:PF21467"
FT ACT_SITE 167
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT ACT_SITE 249
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
SQ SEQUENCE 606 AA; 70393 MW; E2B5978CA6C3C801 CRC64;
MKAVLYLREH QMARFKIGHS FCLDDREFKI LSGAIHYFRV QPEDWYHSLY NLKALGFNTV
ETYLPWNMHE PQKGVFDFQG ILDIEAFLQT AQDLGLYAII RPSPFICAEW EFGGLPAWLL
NENMRIRSSD EAFLQAVASY YDELLPRLTP RLLDNGGNIL MMQVENEYGS YGEDKAYLRA
IRRLMEERGV TCPLFTSDGP WRATLQAGTL IDDDVFVTGN FGSKADYNFA QLQEFFDEHG
KKWPLMCMEF WDGWFNRWKE PIIRRDPDEL AQAVHEVLQQ GSINLYMFHG GTNFGFMNGC
SARGVIDLPQ VTSYDYDALL DERGNPTDKY YAVQRMLKEH YPEHPQMEPL VKESFELRNI
PLSQKVSLFE TLPDLAEPIE SLYPMKMEEL GQNVGYLLYR TWASWDADQE RLRVIDGRDR
MQLYVDGQHI ATQYQTEIGQ DIMVDGQKKA EHQLDILMEN MGRVNYGHKL LADTQQKGIR
TGVCKDLHFL IDWQHYPLPL DHPEKIDFSK GWQEKQPAFY AFDFKMKALK DTYLDLSDFG
KGVVFVNGVS IGRFWNVGPT LSLYIPHSLL REGDNRIIIF ETEGIYSETI HLVNQPTFKI
IKGENL
//
