ID F0GFM3_9BURK Unreviewed; 360 AA.
AC F0GFM3;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Thiamine pyrophosphate protein central region {ECO:0000313|EMBL:EGC99706.1};
DE Flags: Fragment;
GN ORFNames=B1M_35251 {ECO:0000313|EMBL:EGC99706.1};
OS Burkholderia sp. TJI49.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=987057 {ECO:0000313|EMBL:EGC99706.1, ECO:0000313|Proteomes:UP000003049};
RN [1] {ECO:0000313|EMBL:EGC99706.1, ECO:0000313|Proteomes:UP000003049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TJI49 {ECO:0000313|EMBL:EGC99706.1,
RC ECO:0000313|Proteomes:UP000003049};
RX PubMed=23653265; DOI=10.1007/s11274-013-1366-5;
RA Khan A., Asif H., Studholme D.J., Khan I.A., Azim M.K.;
RT "Genome characterization of a novel Burkholderia cepacia complex genomovar
RT isolated from dieback affected mango orchards.";
RL World J. Microbiol. Biotechnol. 29:2033-2044(2013).
CC -!- SIMILARITY: Belongs to the TPP enzyme family.
CC {ECO:0000256|ARBA:ARBA00007812}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGC99706.1}.
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DR EMBL; AEXE01002221; EGC99706.1; -; Genomic_DNA.
DR AlphaFoldDB; F0GFM3; -.
DR Proteomes; UP000003049; Unassembled WGS sequence.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR CDD; cd07035; TPP_PYR_POX_like; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR Gene3D; 3.40.50.1220; TPP-binding domain; 1.
DR InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR012000; Thiamin_PyroP_enz_cen_dom.
DR InterPro; IPR012001; Thiamin_PyroP_enz_TPP-bd_dom.
DR InterPro; IPR045229; TPP_enz.
DR PANTHER; PTHR18968:SF9; 3D-(3,5_4)-TRIHYDROXYCYCLOHEXANE-1,2-DIONE HYDROLASE; 1.
DR PANTHER; PTHR18968; THIAMINE PYROPHOSPHATE ENZYMES; 1.
DR Pfam; PF00205; TPP_enzyme_M; 1.
DR Pfam; PF02776; TPP_enzyme_N; 1.
DR SUPFAM; SSF52467; DHS-like NAD/FAD-binding domain; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 3: Inferred from homology;
FT DOMAIN 4..136
FT /note="Thiamine pyrophosphate enzyme N-terminal TPP-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02776"
FT DOMAIN 222..353
FT /note="Thiamine pyrophosphate enzyme central"
FT /evidence="ECO:0000259|Pfam:PF00205"
FT NON_TER 360
FT /evidence="ECO:0000313|EMBL:EGC99706.1"
SQ SEQUENCE 360 AA; 38308 MW; 0314FCA3AE25F57F CRC64;
MRLTVSQALV RYLAALRAEV VQPDGRTEIL PYCGGVFAIF GHGNVAGLGE ALHAEKDRLP
TFRAHNEQGM ANAAIAFAKA NFRQRMMAAT SSIGPGATNM LTSAALAHVG RLPLLLLPGD
VFVSRLPDPV LQQVEDFEQG DVSANDCFRP VTRYFDRITS PEQLLVALPR AIQVMTDPAQ
CGPVCLALPQ DVQTFAYDWP EDFFAPPLIR MRRPPADMLE LADALDVLKA AKKPLIVAGG
GVLYSQAWDA LRTFADTHGV PVAESQAGKG SLAWDHPLNL GAIGVTGSPA ANRAAAQADV
VLAVGTRLQD FTTGSHALFG QATLLSLNVQ PFDAGKKRGR QLIADARTGL GQLSAALAGW
//
