ID   F0GL51_9BURK            Unreviewed;       433 AA.
AC   F0GL51;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=Xanthine/uracil/vitamin C transporter {ECO:0000313|EMBL:EGC97778.1};
GN   ORFNames=B1M_44934 {ECO:0000313|EMBL:EGC97778.1};
OS   Burkholderia sp. TJI49.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia.
OX   NCBI_TaxID=987057 {ECO:0000313|EMBL:EGC97778.1, ECO:0000313|Proteomes:UP000003049};
RN   [1] {ECO:0000313|EMBL:EGC97778.1, ECO:0000313|Proteomes:UP000003049}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TJI49 {ECO:0000313|EMBL:EGC97778.1,
RC   ECO:0000313|Proteomes:UP000003049};
RX   PubMed=23653265; DOI=10.1007/s11274-013-1366-5;
RA   Khan A., Asif H., Studholme D.J., Khan I.A., Azim M.K.;
RT   "Genome characterization of a novel Burkholderia cepacia complex genomovar
RT   isolated from dieback affected mango orchards.";
RL   World J. Microbiol. Biotechnol. 29:2033-2044(2013).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR005353};
CC       Multi-pass membrane protein {ECO:0000256|PIRNR:PIRNR005353}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697,
CC       ECO:0000256|PIRNR:PIRNR005353}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGC97778.1}.
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DR   EMBL; AEXE01002989; EGC97778.1; -; Genomic_DNA.
DR   AlphaFoldDB; F0GL51; -.
DR   PATRIC; fig|987057.7.peg.6792; -.
DR   BioCyc; BSP987057:G10O5-2026-MONOMER; -.
DR   Proteomes; UP000003049; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR   InterPro; IPR045018; Azg-like.
DR   InterPro; IPR026033; Azg-like_bact_archaea.
DR   InterPro; IPR006043; NCS2.
DR   PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR   PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PIRSF; PIRSF005353; PbuG; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005353};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005353}.
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        53..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        97..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        133..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        194..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        230..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        379..402
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        414..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   433 AA;  45465 MW;  06C0F85F494AB716 CRC64;
     MESIKRYFGF AEAGTDFRTE ILAGVTTFLT MAYIIFVNPA ILGDAGMPKE SVFVATCLVA
     ALASIIMGLY ANYPIACAPG MGLNAYFAYT VVKGMGFTWQ AALGAVFISG CLFLIVTLFR
     VREAIVNGIP KSLRISITAG IGLFLGIISL KTSGVIVGNP ATLVTLGDLH KHDTILAIVG
     FFTIVTLDHL RVRGAILIGI IGVTILSFFF GDNQFHGVFS APPSIDATLF KLDIGAALST
     GIINVILVFF LVELFDATGT LMGVANRAGL LVEGKMNRLN KALLADSTAI VAGSVLGTSS
     TTAYIESASG VQAGGRTGVT AITVAVLFLA CLFIAPLAGV VPAYATAPAL LYVSCLMLRE
     MVEVPWDDAT EAVPAALTAL LMPFTYSIAN GVAFGFIAYG GLKLLTGQGG KVKPIVWIIA
     AVFLFRFFYL GSE
//