ID F0I3F1_STRSA Unreviewed; 384 AA.
AC F0I3F1;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Site-specific DNA-methyltransferase {ECO:0000313|EMBL:EGD28950.1};
GN ORFNames=HMPREF9381_1691 {ECO:0000313|EMBL:EGD28950.1};
OS Streptococcus sanguinis SK72.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=888809 {ECO:0000313|EMBL:EGD28950.1, ECO:0000313|Proteomes:UP000003332};
RN [1] {ECO:0000313|EMBL:EGD28950.1, ECO:0000313|Proteomes:UP000003332}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK72 {ECO:0000313|EMBL:EGD28950.1,
RC ECO:0000313|Proteomes:UP000003332};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGD28950.1}.
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DR EMBL; AEXV01000010; EGD28950.1; -; Genomic_DNA.
DR RefSeq; WP_002905193.1; NZ_GL872376.1.
DR AlphaFoldDB; F0I3F1; -.
DR PATRIC; fig|888809.3.peg.1647; -.
DR HOGENOM; CLU_032119_3_1_9; -.
DR Proteomes; UP000003332; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:EGD28950.1};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000313|EMBL:EGD28950.1}.
FT DOMAIN 45..159
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 384 AA; 43072 MW; 9FFF5FA8B12604C9 CRC64;
MKEKFNLIAT AAAGLEAVVG REIRELGLDC QVENGRIRFE GDVSTIIQTN LWLRAADRIK
IVVGSFPAKT FEELFQGVFA LDWENYIPLG AKFPIAKAKC VKSKLHNEPS VQAISKKAVV
KKLQKHYARP EGVPLQENGA EFRIEVSILK DVVTVMIDTT GSSLFKRGYR ADKGGAPIKE
NMAAAILLLS NWYPDKPLID PTCGSGTFCI EAAMIGMKMA PGLHRSFAFE DWNWVDKDLV
AQARSTVLSQ IDQTIQLDIS GSDIDGRMVE LARKNAEQAG VAEQIHFKQM RLQDLHTDKI
NGVIISNPPY GERLLDDEAV TRLYQEMGET FALLKTWSKF ILTSDEAFES KYGSQSDKKR
KLYNGTLKVD LYQYFGQRVK RQLD
//
