ID F0IKM3_STRSA Unreviewed; 384 AA.
AC F0IKM3;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Site-specific DNA-methyltransferase {ECO:0000313|EMBL:EGD37115.1};
GN ORFNames=HMPREF9383_0675 {ECO:0000313|EMBL:EGD37115.1};
OS Streptococcus sanguinis SK150.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=888811 {ECO:0000313|EMBL:EGD37115.1, ECO:0000313|Proteomes:UP000003530};
RN [1] {ECO:0000313|EMBL:EGD37115.1, ECO:0000313|Proteomes:UP000003530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK150 {ECO:0000313|EMBL:EGD37115.1,
RC ECO:0000313|Proteomes:UP000003530};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGD37115.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEXY01000005; EGD37115.1; -; Genomic_DNA.
DR RefSeq; WP_002908990.1; NZ_GL872442.1.
DR AlphaFoldDB; F0IKM3; -.
DR PATRIC; fig|888811.3.peg.667; -.
DR HOGENOM; CLU_032119_3_1_9; -.
DR Proteomes; UP000003530; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:EGD37115.1};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000313|EMBL:EGD37115.1}.
FT DOMAIN 45..159
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 384 AA; 43026 MW; 1801C795846725F5 CRC64;
MKEKFNLIAT AAAGLEAVVG REIRELGLDC QVENGRVRFE GDVSTIIQTN LWLRAANRIK
IVVGSFPAKT FEELFQGVFA LDWENYLPLG AKFPIAKAKC VKSKLHNEPS VQAISKKAVV
KKLQKHYARP EGVPLQENGA EFRIEVSILK DVVTVMIDTT GSSLFKRGYR ADKGGAPIKE
NMAAAILLLS NWYPDKPLID PTCGSGTFCI EAAMIGMKMA PGLHRSFAFE DWNWVDKDLV
AQARSTALSQ IDQTIQLDIS GSDIDGRMVE LARKNAEQAG VAEQIHFKQM RLQDLHTDKI
NGVIISNPPY GERLLDDETV TRLYQEMGET FAPLKTWSKF ILTSDEAFES KYGSQADKKR
KLYNGTLKVD LYQYFGQRVK RQLD
//
