ID F0LL70_THEBM Unreviewed; 113 AA.
AC F0LL70;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Mannose-6-phosphate isomerase {ECO:0000313|EMBL:ADT83721.1};
GN OrderedLocusNames=TERMP_00744 {ECO:0000313|EMBL:ADT83721.1};
OS Thermococcus barophilus (strain DSM 11836 / MP).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=391623 {ECO:0000313|EMBL:ADT83721.1, ECO:0000313|Proteomes:UP000007478};
RN [1] {ECO:0000313|EMBL:ADT83721.1, ECO:0000313|Proteomes:UP000007478}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11836 / MP {ECO:0000313|Proteomes:UP000007478};
RX PubMed=21217005; DOI=10.1128/JB.01490-10;
RA Vannier P., Marteinsson V.T., Fridjonsson O.H., Oger P., Jebbar M.;
RT "Complete genome sequence of the hyperthermophilic, piezophilic,
RT heterotrophic, and carboxydotrophic archaeon Thermococcus barophilus MP.";
RL J. Bacteriol. 193:1481-1482(2011).
RN [2] {ECO:0007829|PDB:7ZVM}
RP X-RAY CRYSTALLOGRAPHY (1.58 ANGSTROMS) IN COMPLEX WITH MG(2+).
RX PubMed=35955607; DOI=10.3390/ijms23158469;
RA Calio A., Dubois C., Fontanay S., Koza M.M., Hoh F., Roumestand C.,
RA Oger P., Peters J.;
RT "Unravelling the Adaptation Mechanisms to High Pressure in Proteins.";
RL Int. J. Mol. Sci. 23:8469-8469(2022).
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DR EMBL; CP002372; ADT83721.1; -; Genomic_DNA.
DR RefSeq; WP_013467019.1; NC_014804.1.
DR PDB; 7ZVM; X-ray; 1.58 A; A=1-113.
DR AlphaFoldDB; F0LL70; -.
DR SMR; F0LL70; -.
DR GeneID; 10041062; -.
DR KEGG; tba:TERMP_00744; -.
DR PATRIC; fig|391623.17.peg.746; -.
DR eggNOG; arCOG02994; Archaea.
DR HOGENOM; CLU_170082_0_0_2; -.
DR OrthoDB; 23670at2157; -.
DR Proteomes; UP000007478; Chromosome.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR CDD; cd02208; cupin_RmlC-like; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR013096; Cupin_2.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR011051; RmlC_Cupin_sf.
DR PANTHER; PTHR43346; LIGAND BINDING DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14370)-RELATED; 1.
DR PANTHER; PTHR43346:SF1; LIGAND BINDING DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14370)-RELATED; 1.
DR Pfam; PF07883; Cupin_2; 1.
DR SUPFAM; SSF51182; RmlC-like cupins; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:7ZVM};
KW Isomerase {ECO:0000313|EMBL:ADT83721.1};
KW Metal-binding {ECO:0007829|PDB:7ZVM};
KW Reference proteome {ECO:0000313|Proteomes:UP000007478}.
FT DOMAIN 32..100
FT /note="Cupin type-2"
FT /evidence="ECO:0000259|Pfam:PF07883"
FT BINDING 46
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0007829|PDB:7ZVM"
FT BINDING 51
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0007829|PDB:7ZVM"
FT BINDING 85
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0007829|PDB:7ZVM"
SQ SEQUENCE 113 AA; 13364 MW; C4772F28E63AFA64 CRC64;
MKAEIKEFID RGTYRKAPLF EGELPEGSYA QIVEIKPKQT VPKHYHEKQY ELFYIISGQA
KLGIEEREYD AKPGDIFLVK PKTVHWVVNK KEEPFRLFVI KLNYFGDDSV WLE
//
