ID F0QX43_VULM7 Unreviewed; 220 AA.
AC F0QX43;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=orotidine-5'-phosphate decarboxylase {ECO:0000256|ARBA:ARBA00012321};
DE EC=4.1.1.23 {ECO:0000256|ARBA:ARBA00012321};
GN OrderedLocusNames=VMUT_2135 {ECO:0000313|EMBL:ADY02332.1};
OS Vulcanisaeta moutnovskia (strain 768-28).
OC Archaea; Thermoproteota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC Vulcanisaeta.
OX NCBI_TaxID=985053 {ECO:0000313|EMBL:ADY02332.1, ECO:0000313|Proteomes:UP000007485};
RN [1] {ECO:0000313|EMBL:ADY02332.1, ECO:0000313|Proteomes:UP000007485}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=768-28 {ECO:0000313|EMBL:ADY02332.1,
RC ECO:0000313|Proteomes:UP000007485};
RX PubMed=21398550; DOI=10.1128/JB.00237-11;
RA Gumerov V.M., Mardanov A.V., Beletsky A.V., Prokofeva M.I.,
RA Bonch-Osmolovskaya E.A., Ravin N.V., Skryabin K.G.;
RT "Complete genome sequence of 'Vulcanisaeta moutnovskia' strain 768-28, a
RT novel member of the hyperthermophilic crenarchaeal genus vulcanisaeta.";
RL J. Bacteriol. 193:2355-2356(2011).
CC -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo pathway;
CC UMP from orotate: step 2/2. {ECO:0000256|ARBA:ARBA00004861}.
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DR EMBL; CP002529; ADY02332.1; -; Genomic_DNA.
DR RefSeq; WP_013605493.1; NC_015151.1.
DR AlphaFoldDB; F0QX43; -.
DR STRING; 985053.VMUT_2135; -.
DR GeneID; 10289787; -.
DR KEGG; vmo:VMUT_2135; -.
DR eggNOG; arCOG00081; Archaea.
DR HOGENOM; CLU_067069_2_0_2; -.
DR OrthoDB; 94124at2157; -.
DR Proteomes; UP000007485; Chromosome.
DR GO; GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:InterPro.
DR GO; GO:0006207; P:'de novo' pyrimidine nucleobase biosynthetic process; IEA:InterPro.
DR GO; GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
DR CDD; cd04725; OMP_decarboxylase_like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR014732; OMPdecase.
DR InterPro; IPR001754; OMPdeCOase_dom.
DR InterPro; IPR011060; RibuloseP-bd_barrel.
DR PANTHER; PTHR32119; OROTIDINE 5'-PHOSPHATE DECARBOXYLASE; 1.
DR PANTHER; PTHR32119:SF2; OROTIDINE 5'-PHOSPHATE DECARBOXYLASE; 1.
DR Pfam; PF00215; OMPdecase; 1.
DR SMART; SM00934; OMPdecase; 1.
DR SUPFAM; SSF51366; Ribulose-phoshate binding barrel; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239}.
FT DOMAIN 7..211
FT /note="Orotidine 5'-phosphate decarboxylase"
FT /evidence="ECO:0000259|SMART:SM00934"
SQ SEQUENCE 220 AA; 23886 MW; 4A2D1D0671F6C9CB CRC64;
MIIRHNGLIL AFDVDWDTKR SIVFLRGIMD LIDAVKVGWL QLLNIGPNGI KELTSGINTY
FLADIKLGDI AHINEYVIRR LRDLGINGVI MHAVTGRENL NGVAKLSRDL GIDIFLLISM
SSGGELYDLN LDYNVKLGTE LGIAGFVVPA TKPNIIRRVR SMVGNNYQLL SPGVGVQGGK
PGCATASGAD FEIVGRSIIN SESPREVTLS ILSAIKDPRC
//
