ID F0RCN4_CELLC Unreviewed; 635 AA.
AC F0RCN4;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN OrderedLocusNames=Celly_1908 {ECO:0000313|EMBL:ADY29731.1};
OS Cellulophaga lytica (strain ATCC 23178 / DSM 7489 / JCM 8516 / NBRC 14961 /
OS NCIMB 1423 / VKM B-1433 / Cy l20).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Cellulophaga.
OX NCBI_TaxID=867900 {ECO:0000313|EMBL:ADY29731.1, ECO:0000313|Proteomes:UP000007487};
RN [1] {ECO:0000313|EMBL:ADY29731.1, ECO:0000313|Proteomes:UP000007487}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23178 / DSM 7489 / JCM 8516 / NBRC 14961 / NCIMB 1423 /
RC VKM B-1433 / Cy l20 {ECO:0000313|Proteomes:UP000007487};
RX PubMed=21677859; DOI=10.4056/sigs.1774329;
RA Pati A., Abt B., Teshima H., Nolan M., Lapidus A., Lucas S., Hammon N.,
RA Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S.,
RA Liolios K., Pagani I., Mavromatis K., Ovchinikova G., Chen A.,
RA Palaniappan K., Land M., Hauser L., Jeffries C.D., Detter J.C.,
RA Brambilla E.M., Kannan K.P., Rohde M., Spring S., Goker M., Woyke T.,
RA Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C.,
RA Klenk H.P., Ivanova N.;
RT "Complete genome sequence of Cellulophaga lytica type strain (LIM- 21).";
RL Stand. Genomic Sci. 4:221-232(2011).
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DR EMBL; CP002534; ADY29731.1; -; Genomic_DNA.
DR RefSeq; WP_013621476.1; NC_015167.1.
DR AlphaFoldDB; F0RCN4; -.
DR STRING; 867900.Celly_1908; -.
DR KEGG; cly:Celly_1908; -.
DR eggNOG; COG0365; Bacteria.
DR HOGENOM; CLU_000022_3_6_10; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000007487; Chromosome.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ADY29731.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007487}.
FT DOMAIN 12..68
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 71..461
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 519..598
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 635 AA; 71775 MW; FF1DF0E4F60F8FAF CRC64;
MSNYHIKHLE EYFQVYRKSV RNPEAFWEEI AEEHFLWRKK WDNVLSWDFS KPEVKWFENA
KLNITENCID RHLTTRGEKT AILFEPNNPN EEAQHISYYE LHKRVCKMAN VLKENGVKKG
DRVCIYLPMI PELAVSLLAC ARIGAIHSVV FAGFSSNALA TRINDSDCKL VITSDGSFRG
KKSIDLKGIV DVALNDCPGV KTVLVAKRTN AEITMVEGRD KWLQPLLDEA YGDCVAEIMD
AEDPLFILYT SGSTGTPKGM VHTTGGYMVY TAYTFKNIFQ YKENDIYWCT ADIGWITGHS
YIVYGPLANG ATTVMFEGVP SYPDFGRFWE VVEKHKVTQF YTAPTAIRAL AKENMDFVEN
HDLSSLKVLG SVGEPINEEA WHWYNNNVGK NNSPIVDTWW QTETGGIMIS PIPYVTPTTP
TYATLPFIGI QPALMDENGQ EVKGNQVEGR LCIKYPWPSI ARTIWGNHER YRDTYFSAYK
DKYFTGDGAL RDGVGYYRIT GRVDDVIIVS GHNLGTAPIE DTINEHPAVA ESAIVGFPHD
VKGNALYGYV ILKEFGETRD RDNLRNEINQ QITEHIGPIA KLDKIQFVTG LPKTRSGKIM
RRILRKIASN DTGNLGDIST LLNPEIVKEI MDNSL
//
