ID F0RRU8_SPHGB Unreviewed; 808 AA.
AC F0RRU8;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:ADY14553.1};
GN OrderedLocusNames=SpiBuddy_2744 {ECO:0000313|EMBL:ADY14553.1};
OS Sphaerochaeta globosa (strain ATCC BAA-1886 / DSM 22777 / Buddy)
OS (Spirochaeta sp. (strain Buddy)).
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Sphaerochaetaceae;
OC Sphaerochaeta.
OX NCBI_TaxID=158189 {ECO:0000313|EMBL:ADY14553.1, ECO:0000313|Proteomes:UP000008466};
RN [1] {ECO:0000313|Proteomes:UP000008466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1886 / DSM 22777 / Buddy
RC {ECO:0000313|Proteomes:UP000008466};
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Zeytun A., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Ivanova N., Mikhailova N., Pagani I., Ritalahti K.M., Loeffler F.E.,
RA Woyke T.;
RT "Complete sequence of Spirochaeta sp. Buddy.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002541; ADY14553.1; -; Genomic_DNA.
DR RefSeq; WP_013608397.1; NC_015152.1.
DR AlphaFoldDB; F0RRU8; -.
DR STRING; 158189.SpiBuddy_2744; -.
DR KEGG; sbu:SpiBuddy_2744; -.
DR eggNOG; COG2200; Bacteria.
DR eggNOG; COG2202; Bacteria.
DR HOGENOM; CLU_000445_70_20_12; -.
DR OrthoDB; 9805474at2; -.
DR Proteomes; UP000008466; Chromosome.
DR CDD; cd01948; EAL; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08447; PAS_3; 2.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008466}.
FT DOMAIN 197..249
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 271..325
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 328..380
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 410..542
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 551..808
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 808 AA; 91115 MW; 479361DE7765281B CRC64;
MAKKLLVVGS SAEDASLIGT AMAGYEVVLA KDGKQALELA AGLSDLVLII IDAIANTFDA
LLLLHTLEQN PRYAIMLITD SGDGVSLLHQ PLTSDAVSKQ VQQVLRKDHS KLLNEQSFLF
NAIFWQAPIG ISISHGIGPI DGPINEVFSV NPRFEAITGR TSQELKAIGW AVITHPDDLE
ADLTQFKRLQ AGEIQSYSLE KRYIKPDGTY VWVSLVVAAL KIQSDHSYSH ICLVQDISQR
KKAEQLLAES ERSKSVLLSH LPGLAYRTKY DRDWTVLYVS KGCKALTGYD SESLLGNRDL
SFNDLIVPCY QEDIRREWDR VLPLHQMFTY EYEIITRDGK RKWVWENGQG FYTKQGEVEE
LEGIILDISN RKNVEQELMY NNEHDIWTGL FNRQYLERLL RLDAQLHPSL KRAVLAVNIS
ALHFANMTYG FQYTQEVVKK VSSALQVLTS EQCLLCKTHE YRFSFYIKNY HTKQDLIDFC
KRISSLLESF LIIEGINWGI GIVEIKKETA EDVEQLLRNL LVASEKALQQ LQGDICCCFF
DAAMEEQLYQ EEEITAELSR IASGEGSGSL FLNYQPILEL ATNKIVGFEA LARLQIPSLG
LISPLQFIPI TEKTKLIIPL GDSIILQALR FLNTLQNSGY ADIGISINIS AIQLLKHDFI
THLLQMISSM QVDPQNICLE ITESVFASNY QDINKVLGHL QSQGIQIAID DFGTGYSSLA
RERELNINCL KIDKFFIDKL MTLTEEEAIT GDIISLAHKL GHCVVAEGIE HERQLQYLRK
FGCDKIQGFL FSKPLDEQAA LSFLKAQT
//
