ID F0UG96_AJEC8 Unreviewed; 381 AA.
AC F0UG96;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=C2H2 finger domain-containing protein {ECO:0000313|EMBL:EGC45091.1};
GN Name=KIN17 {ECO:0000313|EMBL:QSS55862.1};
GN ORFNames=HCEG_04306 {ECO:0000313|EMBL:EGC45091.1}, I7I53_03859
GN {ECO:0000313|EMBL:QSS55862.1};
OS Ajellomyces capsulatus (strain H88) (Darling's disease fungus) (Histoplasma
OS capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=544711 {ECO:0000313|Proteomes:UP000008142};
RN [1] {ECO:0000313|Proteomes:UP000008142}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H88 {ECO:0000313|Proteomes:UP000008142};
RA Champion M., Cuomo C., Ma L.-J., Henn M.R., Sil A., Goldman B., Young S.K.,
RA Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B.,
RA Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Klein B.,
RA McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA San-Blas G., Taylor J., Mendoza L., Galagan J., Nusbaum C., Birren B.;
RT "Annotation of Ajellomyces capsulatus strain H88.";
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EGC45091.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H88 {ECO:0000313|EMBL:EGC45091.1};
RG The Broad Institute Genome Sequencing Platform;
RA Champion M., Cuomo C., Ma L.-J., Henn M.R., Sil A., Goldman B., Young S.K.,
RA Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B.,
RA Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Klein B.,
RA McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA San-Blas G., Taylor J., Mendoza L., Galagan J., Nusbaum C., Birren B.;
RT "Annotation of Ajellomyces capsulatus strain H88.";
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QSS55862.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=H88 {ECO:0000313|EMBL:QSS55862.1};
RA Voorhies M., Cohen S., Shea T.P., Petrus S., Munoz J.F., Poplawski S.,
RA Goldman W.E., Michael T., Cuomo C.A., Sil A., Beyhan S.;
RT "Chromosome-level genome assembly of a human fungal pathogen reveals
RT clustering of transcriptionally co-regulated genes.";
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DS990638; EGC45091.1; -; Genomic_DNA.
DR EMBL; CP069105; QSS55862.1; -; Genomic_DNA.
DR AlphaFoldDB; F0UG96; -.
DR STRING; 544711.F0UG96; -.
DR VEuPathDB; FungiDB:I7I53_03859; -.
DR HOGENOM; CLU_030065_0_1_1; -.
DR OMA; IFISWID; -.
DR Proteomes; UP000008142; Unassembled WGS sequence.
DR Proteomes; UP000663419; Chromosome 4.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.10.2030; DNA/RNA-binding protein Kin17, conserved domain; 1.
DR InterPro; IPR019447; DNA/RNA-bd_Kin17_WH-like_dom.
DR InterPro; IPR037321; KIN17-like.
DR InterPro; IPR038254; KIN17_WH-like_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR12805:SF0; DNA_RNA-BINDING PROTEIN KIN17; 1.
DR PANTHER; PTHR12805; KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG; 1.
DR Pfam; PF10357; Kin17_mid; 1.
DR SMART; SM01253; Kin17_mid; 1.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008142}.
FT DOMAIN 28..50
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT REGION 157..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 352..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..209
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..238
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..255
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..317
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..366
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 381 AA; 42701 MW; 7AEC5C447078A4F8 CRC64;
MPRAEVGSTK YLSNKLKSKG LQRLRWYCQV CERQMRDENG FKCHTQSESH VRQMLLVGED
PRKYIQQYSN EFLSDFLKQL RTSHGEKAIN INHFYQEYIA NKEHIHMNAT RWPSLTEFAK
YLGREGICRV EEGEKGIFIS WIDNSPDALR RQDALRKKEM QDRGDEERER RMIEEQVRRA
QRDREIAGRE PPRKDDTDAA PKEWQPTEGE KIKLNFASSK GVASSLSTSA SPAPVDTTSP
ALTPAPAPAP APAPTPGDRN GEQSPAQNSS PSSKPSTTTP APPTTNQSTL PMTASATQSD
RSSTSLKVGT VTSKPKNVFA AASKKNALAA ATKKKKVEAP SKPLTATERI MKEDMERKRS
REERSKGFNN GGINFKRQKI A
//
