ID F0UKJ2_AJEC8 Unreviewed; 572 AA.
AC F0UKJ2;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Sugar transporter {ECO:0000313|EMBL:EGC45946.1};
GN ORFNames=HCEG_05161 {ECO:0000313|EMBL:EGC45946.1};
OS Ajellomyces capsulatus (strain H88) (Darling's disease fungus) (Histoplasma
OS capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=544711 {ECO:0000313|Proteomes:UP000008142};
RN [1] {ECO:0000313|Proteomes:UP000008142}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H88 {ECO:0000313|Proteomes:UP000008142};
RA Champion M., Cuomo C., Ma L.-J., Henn M.R., Sil A., Goldman B., Young S.K.,
RA Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B.,
RA Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Klein B.,
RA McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA San-Blas G., Taylor J., Mendoza L., Galagan J., Nusbaum C., Birren B.;
RT "Annotation of Ajellomyces capsulatus strain H88.";
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000256|ARBA:ARBA00010992}.
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DR EMBL; DS990639; EGC45946.1; -; Genomic_DNA.
DR AlphaFoldDB; F0UKJ2; -.
DR VEuPathDB; FungiDB:I7I53_04836; -.
DR HOGENOM; CLU_001265_52_2_1; -.
DR OMA; PTWIGVC; -.
DR Proteomes; UP000008142; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR CDD; cd17316; MFS_SV2_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23511; SYNAPTIC VESICLE GLYCOPROTEIN 2; 1.
DR PANTHER; PTHR23511:SF5; TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G03500)-RELATED; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008142};
KW Sugar transport {ECO:0000313|EMBL:EGC45946.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 110..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 425..444
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 456..474
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 545..564
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 112..567
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 27..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 572 AA; 61468 MW; B8FCA2FF82D84C78 CRC64;
MPLLVNPFRQ QDHSSFPGVV VPLAQAPRHR KFSHSNPNPN PGDGDKADNV AEKGSSSSLS
DRQYSGWTVE AIRAEVESDA ATSGRDTAYD RKSKVINLAI QDIGMGKYQW QLFVLCGFGW
LADNLWLQGV ALTLPSLSAE FGIGASYVRF TTCSLFVGLC VGAVFWGTAS DMIGRRLAFN
LTLLITGVFG LAAGGSPTWV GVCSMFACLG LGVGGNLPVD GALFLEFLPF ASGNLLTMLS
IWWPVGTLVG SMIAWGLIPN FSCGPSAAIC TKENNMGWRY LVITLGGLTF VMFLCRFFLF
HLYESPKFLL SRGRQADAVA TVHAIAYKNG AKTWLTSEIL NEIGGYPEEI PAEEQTLSSA
EVIKRQFAKF SGQRIAPLFA TRKLGFTTVL LWICWATIGM GYPLFNAFLP QYLGNNGETP
VSIVYRNYAI TAVVGVPGSI LACYTVDIPY IGRKGTMAIS TALTAVTLFC FTISTDPDVQ
LACSSLEAFF QNIMYGVLYA YTPEVFPAPN RGTGTGIASC LNRICGLLAP IVAIYGGSAN
PKAPVYASGG LMLAAFVAMV LLPIETRGRA SL
//
