ID F0UU40_AJEC8 Unreviewed; 1674 AA.
AC F0UU40;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=BTB domain and ankyrin repeat protein {ECO:0000313|EMBL:EGC49417.1};
GN ORFNames=HCEG_08632 {ECO:0000313|EMBL:EGC49417.1};
OS Ajellomyces capsulatus (strain H88) (Darling's disease fungus) (Histoplasma
OS capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=544711 {ECO:0000313|Proteomes:UP000008142};
RN [1] {ECO:0000313|Proteomes:UP000008142}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H88 {ECO:0000313|Proteomes:UP000008142};
RA Champion M., Cuomo C., Ma L.-J., Henn M.R., Sil A., Goldman B., Young S.K.,
RA Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B.,
RA Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Klein B.,
RA McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA San-Blas G., Taylor J., Mendoza L., Galagan J., Nusbaum C., Birren B.;
RT "Annotation of Ajellomyces capsulatus strain H88.";
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DS990643; EGC49417.1; -; Genomic_DNA.
DR STRING; 544711.F0UU40; -.
DR HOGENOM; CLU_002285_0_0_1; -.
DR OMA; RIPVHEF; -.
DR Proteomes; UP000008142; Unassembled WGS sequence.
DR CDD; cd18186; BTB_POZ_ZBTB_KLHL-like; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR22872:SF2; BTB_POZ DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR22872; BTK-BINDING PROTEIN-RELATED; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF13540; RCC1_2; 1.
DR PRINTS; PR00633; RCCNDNSATION.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00225; BTB; 2.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS50012; RCC1_3; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008142};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 345..398
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 399..459
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT DOMAIN 914..943
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 25..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 59..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1223..1455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1531..1674
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1227..1246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1258..1272
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1304..1327
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1328..1407
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1421..1449
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1596..1621
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1674 AA; 183070 MW; BFDEC1189BDB3595 CRC64;
MSSKLWQYFL QDDVQSFTRF LADTTSSNTQ RKSSNNASAF SGHGSSGAAL GTSPGSFLKG
SRPTAASSLK QPSSTTRNAP VILTRADVNV KDRYGRTLLH LIASSQKENG IEFASALLEV
PFVDIYAQDL ESGWTALHRA LYAGNVAIAQ ALLARDIRDA TDFRPPGGVP HPSGGLIKIK
DREGNSPFDV FGATILPRDI NNASGYKSNS DSDNAASTES SILSETEIDH ETAGPANVKP
VVNILGDEVF TFGSNKNLNL GLGDEDDRQF PERIGLTRPD HLLYTFNRDH RVVRAARRGS
DPHAEESDIH SVNDIPTLVR ARPIIYRQIV MSKLHTGIIT DDPESNLFMC GFGPGGRLGT
GDQGTRFSFV CIEGGGLAGK KVVSLALGQD HSIAVSEQGE VFSWGSNKYG QLGYALPKTS
HKNDVPIQTT PRQIFNPFKK EAIIGAAASA IHSVVFTPTG LYTFGKNEGQ LGLIDADARS
LETQTIPRRV GASLFSSPIV MVSAIDRATT CLLENHEVWV FTHYGYSKIV FPLDGASSFI
RNSFMSTRYG LSTNHISKIT SGGNTICAMS TFGEVYTVHV SRKADTSSTA SSTTNPAKIR
NSLPQPSCMW SIKKSHMAVR DVDVGQDGSI ILCTESGSAW RKEKRAKIKE ADGKTTETSR
LKDYKFVRVP GLSRVVAVRS NAFGAYAVSQ RSCDVAKEQI MIDRPSIWDD FWPLLAFKSI
LRARDSGDTL VMSVDVVIRN TLIEPCSLES EIKSTLDDAA RSDSFRPIVW VSTTASDVRI
PAHEFILAGR SSVLRRALSE FRKSYYHSVP DTFDVEYDKN GQVSIKFHDV DFLSIFNLVL
YMYADKVYDM WTLVRHSTKH AAQYKRVRIE VLKLATALEL RELERAARFM ILPRKSLHIN
MERAYEDPNL FGCSDVVIEL DGGNASAHRQ ILCARCPFFN GLFYGRSGGV WLAGRRDGVS
DSGVDPVRVD LKHIRLGIFK FALRHIYADT DDELFEDVKF DELDDLIDLV IDVMAVANEL
MLDRLAQICQ KLLGRFVNNR NAALEYICLN LEAMLENRLL DDLDDDLFCE LDAVCRANQL
TCQPVSRGRN SEDYVAERYP EVIPLLEQDR QRRIDSMRLR SRLHEDELRE SKFRTGTSDK
GGVIPPLSVK IRQSEPVLRE AESIEEASPA LKSKQSTGDL IFHMDDDHLL PFNQHEVSIQ
PSRKQIDSMD VERRPLQMEE KIQDTGAKMS AASTDPDSSS TTLLAKSHER GPAGAPWSSV
GPSNTKTGLT DIMAETLGSH PSGAGINISP RRDAPVTSKL IPSKLSQKER KKLQQQHARE
VFEQRETSKS KPSPPWQTVA SRSSPAPAST PAESQPTMNV STPARTPSKP PMTLRQTVAG
VPSPQSSTPN PAPQKQQHAQ ETRLPPSTPK GSPLPTLKAE SLPRQPSSSA TPPLTTPNQT
ASRSQPYAIT TRNRDDHHRY QQQFNYSSPS PSSSSFSLAY ILEQQQIEKD VIREAATAKH
KLQDIQLEQE FQEWWDQESR RVREEVEKAE AAAARRHVAV GSGSGRGKGK RGRGGGGGGG
GDASGGGRGG SARGPATGSA QARSDRGRRG GGAMGNISNT IATTSNDEES PASQLQVQSA
AADENGRRDV SDRGKGGGRG QSHSLGHSRG RGGGGGGSRI GPRGKGKERA VSTS
//
