ID F0UVX7_AJEC8 Unreviewed; 110 AA.
AC F0UVX7;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Calcium-binding protein {ECO:0000313|EMBL:EGC50054.1};
GN ORFNames=HCEG_09269 {ECO:0000313|EMBL:EGC50054.1};
OS Ajellomyces capsulatus (strain H88) (Darling's disease fungus) (Histoplasma
OS capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=544711 {ECO:0000313|Proteomes:UP000008142};
RN [1] {ECO:0000313|Proteomes:UP000008142}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H88 {ECO:0000313|Proteomes:UP000008142};
RA Champion M., Cuomo C., Ma L.-J., Henn M.R., Sil A., Goldman B., Young S.K.,
RA Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B.,
RA Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Klein B.,
RA McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA San-Blas G., Taylor J., Mendoza L., Galagan J., Nusbaum C., Birren B.;
RT "Annotation of Ajellomyces capsulatus strain H88.";
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0007829|PDB:7R79}
RP X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) OF 33-110, AND DISULFIDE BONDS.
RX PubMed=35731824; DOI=10.1371/journal.ppat.1010417;
RA Azimova D., Herrera N., Duvenage L., Voorhies M., Rodriguez R.A.,
RA English B.C., Hoving J.C., Rosenberg O., Sil A.;
RT "Cbp1, a fungal virulence factor under positive selection, forms an
RT effector complex that drives macrophage lysis.";
RL PLoS Pathog. 18:e1010417-e1010417(2022).
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DR EMBL; DS990644; EGC50054.1; -; Genomic_DNA.
DR PDB; 7R79; X-ray; 1.60 A; A/B/C/D=33-110.
DR AlphaFoldDB; F0UVX7; -.
DR SMR; F0UVX7; -.
DR STRING; 544711.F0UVX7; -.
DR HOGENOM; CLU_2170308_0_0_1; -.
DR Proteomes; UP000008142; Unassembled WGS sequence.
DR Gene3D; 1.10.1740.120; -; 1.
DR InterPro; IPR022013; CBP.
DR Pfam; PF12192; CBP; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:7R79};
KW Reference proteome {ECO:0000313|Proteomes:UP000008142};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..110
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003262312"
FT DOMAIN 33..108
FT /note="Fungal calcium binding protein"
FT /evidence="ECO:0000259|Pfam:PF12192"
FT DISULFID 60..108
FT /evidence="ECO:0007829|PDB:7R79"
FT DISULFID 65..105
FT /evidence="ECO:0007829|PDB:7R79"
FT DISULFID 76..93
FT /evidence="ECO:0007829|PDB:7R79"
SQ SEQUENCE 110 AA; 11111 MW; D37CA4866B3DCB82 CRC64;
MLFSKVIAPA FILLGTASAA PGGLVPENAS KRDQPSVGDA FDKYNEAVKV FTQLSSAANC
DWPACLSSLS ASSAACIAAI GELGLDIPLD LACAATATTS ATQACKGCLW
//
