ID   F0V9I4_NEOCL            Unreviewed;      1201 AA.
AC   F0V9I4;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   24-JAN-2024, entry version 38.
DE   SubName: Full=Sel1 domain protein repeat-containing protein,related {ECO:0000313|EMBL:CBZ50409.1};
GN   ORFNames=NCLIV_008780 {ECO:0000313|EMBL:CBZ50409.1};
OS   Neospora caninum (strain Liverpool).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Sarcocystidae; Neospora.
OX   NCBI_TaxID=572307 {ECO:0000313|EMBL:CBZ50409.1, ECO:0000313|Proteomes:UP000007494};
RN   [1] {ECO:0000313|Proteomes:UP000007494}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Liverpool {ECO:0000313|Proteomes:UP000007494};
RX   PubMed=22457617; DOI=10.1371/journal.ppat.1002567;
RA   Reid A.J., Vermont S.J., Cotton J.A., Harris D., Hill-Cawthorne G.A.,
RA   Konen-Waisman S., Latham S.M., Mourier T., Norton R., Quail M.A.,
RA   Sanders M., Shanmugam D., Sohal A., Wasmuth J.D., Brunk B., Grigg M.E.,
RA   Howard J.C., Parkinson J., Roos D.S., Trees A.J., Berriman M., Pain A.,
RA   Wastling J.M.;
RT   "Comparative genomics of the apicomplexan parasites Toxoplasma gondii and
RT   Neospora caninum: Coccidia differing in host range and transmission
RT   strategy.";
RL   PLoS Pathog. 8:e1002567-e1002567(2012).
CC   -!- SIMILARITY: Belongs to the sel-1 family.
CC       {ECO:0000256|ARBA:ARBA00038101}.
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DR   EMBL; FR823383; CBZ50409.1; -; Genomic_DNA.
DR   RefSeq; XP_003880443.1; XM_003880394.1.
DR   AlphaFoldDB; F0V9I4; -.
DR   GeneID; 13441435; -.
DR   VEuPathDB; ToxoDB:NCLIV_008780; -.
DR   eggNOG; KOG1550; Eukaryota.
DR   InParanoid; F0V9I4; -.
DR   OrthoDB; 1378605at2759; -.
DR   Proteomes; UP000007494; Chromosome III.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR006597; Sel1-like.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR11102:SF147; FIBRONECTIN TYPE-II DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR11102; SEL-1-LIKE PROTEIN; 1.
DR   Pfam; PF08238; Sel1; 8.
DR   SMART; SM00671; SEL1; 7.
DR   SUPFAM; SSF81901; HCP-like; 3.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007494};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        911..931
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          26..91
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          183..207
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          447..483
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          950..1201
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        29..58
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        59..91
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        961..1050
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1088..1146
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1201 AA;  127703 MW;  7629594444FB021D CRC64;
     MLPLLAFPPS FASSAGILLA NAEDIDAERD MSPGEDSDEA DLFESFLEEE DEEAFPSEDG
     FGEDARFSET SREEIESGPK AEEVPERSED ARRRDPFVYA MDTMELEGRS DRVYDLFVHC
     SATDVRCQYE LGVFYFLGIP PLPARNLTAS LVLWHVAALG GSADAQYGLA LLHSNLRDLP
     PLPSFPSASA SPPATREREK SPQHAPASAA LPSVFVNEDL TVVLEGDGAA LDFSAIALYS
     ETLVRQYEDA QARHASLWTL PLRVLERCMS LLSAARDGLL GVAPRGLSEE ELEAIYLSRP
     ASGDQGGGRQ RAQDGLPAGA VYDEARAADQ LTNEKADLPV RSLPTFAANP GLPLAFLYSA
     STSEHPGAAM ALATRLRLAT ANVPLRQSQS CTGAVNFYLP YARRVAMSYG SGIPQAPEFL
     RFHSPPMSVS SHSTGSEGLF RFLPSLAAGS PNRRRDAGAP RPSEGRDTRR APPNSPLSRR
     QHSSPDLEVI LELARRGNPA MQLALGKRLL FGVDGLEQDV ERAREFLLEA AEAGRSEAGA
     LLGYLDALGV GRETNVTAAT VAFLEAAAED RHPIALNGLG YLHFFGSDLV ERNELAAFHL
     FNISASHAFP DAETNLAAMY VTGHGHSQSF VKAMQAYTRA LQAGSTGAAY ALGLMHLNGL
     GAVRECSVAT ALLKRVCEKG GYVTKNLQKA YTLYEQGRFD EAAFHLLLLA EAGHEVSQTN
     LAFMLDGGLT DLFFDGSIGR KRLHAQRFYQ LAAQQGSPLA ELRLGDYAYF GHGVQKEIRA
     RHPSRPLLDD EGNDMSEWIS ESYEAFAPAV PNPRVAVGHY LRVAEMSTDE KWQAPYVAKA
     SFNLGFMRLT GIGLPQDFSV ARNHFERSLE ADPAAPKAPV YLALGLLMLL RFREEVDLNE
     VAQALLEDSR VILLVLIFLI MACLLVLRIL AKRLHPPPSD LFFAYDARHG SPPRLSPPTP
     TSPSSSSSSS SSSSSSSPSS SPSSSSSSSS SSFSSSSSSS SPSSSSSSSS SSSSSSSSSS
     LSSSSSSSSS SSSSSSSSSS SSSSSPVPSE DFGLSAPPAS RATEGSLPSF FEARARELAP
     DLRQRRMTPD TVVSSLSSSS SSASSSSSSS SSSASSSSSS SSSSACVAES GSDEVECRQQ
     NGANASPRAA GEPGAALEPN GTVTDERLIR AQLLEAAAAR RGRTPGGLRS DKQAGATSED
     I
//