ID F0VDN3_NEOCL Unreviewed; 728 AA.
AC F0VDN3;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Myosin motor domain-containing protein {ECO:0000259|PROSITE:PS51456};
GN ORFNames=NCLIV_016180 {ECO:0000313|EMBL:CBZ51826.1};
OS Neospora caninum (strain Liverpool).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Neospora.
OX NCBI_TaxID=572307 {ECO:0000313|EMBL:CBZ51826.1, ECO:0000313|Proteomes:UP000007494};
RN [1] {ECO:0000313|Proteomes:UP000007494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|Proteomes:UP000007494};
RX PubMed=22457617; DOI=10.1371/journal.ppat.1002567;
RA Reid A.J., Vermont S.J., Cotton J.A., Harris D., Hill-Cawthorne G.A.,
RA Konen-Waisman S., Latham S.M., Mourier T., Norton R., Quail M.A.,
RA Sanders M., Shanmugam D., Sohal A., Wasmuth J.D., Brunk B., Grigg M.E.,
RA Howard J.C., Parkinson J., Roos D.S., Trees A.J., Berriman M., Pain A.,
RA Wastling J.M.;
RT "Comparative genomics of the apicomplexan parasites Toxoplasma gondii and
RT Neospora caninum: Coccidia differing in host range and transmission
RT strategy.";
RL PLoS Pathog. 8:e1002567-e1002567(2012).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; FR823387; CBZ51826.1; -; Genomic_DNA.
DR RefSeq; XP_003881859.1; XM_003881810.1.
DR AlphaFoldDB; F0VDN3; -.
DR GeneID; 13444456; -.
DR VEuPathDB; ToxoDB:NCLIV_016180; -.
DR eggNOG; KOG0160; Eukaryota.
DR InParanoid; F0VDN3; -.
DR OrthoDB; 1094820at2759; -.
DR Proteomes; UP000007494; Chromosome VI.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF706; MYOSIN-11; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW Reference proteome {ECO:0000313|Proteomes:UP000007494}.
FT DOMAIN 67..660
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 622..644
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT BINDING 161..168
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 728 AA; 80970 MW; 0C6FE37C6C77E82A CRC64;
MKIWTANAPA VHANPDECFA LCMILPESTE TVLHLKQVDP PPDSPEAEAF TITPDEAFNA
NLGIEVADFA DIGLLPHKNC AAVLAFLKER YLQDLIYTTA DPLLVAVNPF KDLKNTTPEW
LRLYSDAPDV DKLAPHVFRV ARTALERLSA FMASQTIIVS GESGAGKTEA TKQIMSFFAS
GQPGEFSHQR IQDAVIAANP VLEAFGNAKT VRNNNSSRFG RFMQLQLGER GGIQYGSIRN
FLLEKVRVTS QEQNERSYHI FYQLVKGAEG SRRSQLSLLK IEEYTYLSKN GGCYDCPGID
DVQEYKEVND SFRSMGLGAE EIDSIWSIVA GVLLLGNVQL EGYETDSQHN AAALAAGAEA
TLQKCCALLF LDENAVKKEI LYKVKTIGDQ EIESPNSLTD ALINRDSLAK AVYEKLFDWV
VRRVNVTIEP PQGFGIFMGM LDIFGFEVFE HNSLEQLLIN ITNEELQKNF IQIVFARETK
LYYDEGIGNV KITWTDNESV IKALCGKSSS VLAILEDKSL APGGTDEAIV TSMSKALGYS
DVWKPGRKNP RTCFCICHTI ADIQYDATGF IEKNKDLLKP ELCAILQASP NKVTKALFEG
VVMEKGKIAK GQLIASQFMR SLSALMDLIS STEPHFIRCL KPNETKKPHD WSNGKVLAQI
GNTMVFIKPD AVRELTQKMR LVVVAWEPLI RVLEACYSRC LKLRAISDKV QWAVRIQAQI
RKARVLTV
//
