ID F0VEM6_NEOCL Unreviewed; 1288 AA.
AC F0VEM6;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 57.
DE SubName: Full=Selenophosphate synthase, related {ECO:0000313|EMBL:CBZ52170.1};
DE EC=2.7.9.3 {ECO:0000313|EMBL:CBZ52170.1};
GN ORFNames=BN1204_019590 {ECO:0000313|EMBL:CEL66136.1}, NCLIV_019590
GN {ECO:0000313|EMBL:CBZ52170.1};
OS Neospora caninum (strain Liverpool).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Neospora.
OX NCBI_TaxID=572307 {ECO:0000313|EMBL:CBZ52170.1, ECO:0000313|Proteomes:UP000007494};
RN [1] {ECO:0000313|EMBL:CBZ52170.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:CBZ52170.1};
RA Aslett M.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBZ52170.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:CBZ52170.1};
RA Reid A.J., Sohal A., Harris D., Quail M., Sanders M., Berriman M.,
RA Wastling J.M., Pain A.;
RT "Comparative genomics and transcriptomics of Neospora caninum and
RT Toxoplasma gondii.";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000007494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|Proteomes:UP000007494};
RX PubMed=22457617; DOI=10.1371/journal.ppat.1002567;
RA Reid A.J., Vermont S.J., Cotton J.A., Harris D., Hill-Cawthorne G.A.,
RA Konen-Waisman S., Latham S.M., Mourier T., Norton R., Quail M.A.,
RA Sanders M., Shanmugam D., Sohal A., Wasmuth J.D., Brunk B., Grigg M.E.,
RA Howard J.C., Parkinson J., Roos D.S., Trees A.J., Berriman M., Pain A.,
RA Wastling J.M.;
RT "Comparative genomics of the apicomplexan parasites Toxoplasma gondii and
RT Neospora caninum: Coccidia differing in host range and transmission
RT strategy.";
RL PLoS Pathog. 8:e1002567-e1002567(2012).
RN [4] {ECO:0000313|EMBL:CEL66136.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:CEL66136.1};
RX PubMed=25875305; DOI=10.1371/journal.pone.0124473;
RA Ramaprasad A., Mourier T., Naeem R., Malas T.B., Moussa E., Panigrahi A.,
RA Vermont S.J., Otto T.D., Wastling J., Pain A.;
RT "Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV
RT Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel
RT Transcript Features.";
RL PLoS ONE 10:e0124473-e0124473(2015).
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DR EMBL; FR823388; CBZ52170.1; -; Genomic_DNA.
DR EMBL; LN714481; CEL66136.1; -; Genomic_DNA.
DR RefSeq; XP_003882202.1; XM_003882153.1.
DR GeneID; 13443935; -.
DR VEuPathDB; ToxoDB:NCLIV_019590; -.
DR eggNOG; KOG3939; Eukaryota.
DR InParanoid; F0VEM6; -.
DR OrthoDB; 177624at2759; -.
DR Proteomes; UP000007494; Chromosome VIIa.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0004756; F:selenide, water dikinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.100; -; 2.
DR Gene3D; 3.90.650.10; PurM-like C-terminal domain; 1.
DR Gene3D; 3.30.1330.10; PurM-like, N-terminal domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR010918; PurM-like_C_dom.
DR InterPro; IPR036676; PurM-like_C_sf.
DR InterPro; IPR016188; PurM-like_N.
DR InterPro; IPR036921; PurM-like_N_sf.
DR InterPro; IPR004536; SPS/SelD.
DR PANTHER; PTHR10256:SF0; INACTIVE SELENIDE, WATER DIKINASE-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR10256; SELENIDE, WATER DIKINASE; 1.
DR Pfam; PF00586; AIRS; 1.
DR Pfam; PF02769; AIRS_C; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR SUPFAM; SSF56042; PurM C-terminal domain-like; 1.
DR SUPFAM; SSF55326; PurM N-terminal domain-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Reference proteome {ECO:0000313|Proteomes:UP000007494};
KW Selenium {ECO:0000256|ARBA:ARBA00023266};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CBZ52170.1}.
FT DOMAIN 454..519
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 878..973
FT /note="PurM-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00586"
FT DOMAIN 1017..1092
FT /note="PurM-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02769"
FT REGION 291..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 611..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 740..769
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 976..1002
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1108..1131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 740..755
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 976..994
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1288 AA; 136355 MW; 2B51C60BB9007095 CRC64;
MGQTGKGGCS MQGLGSIARD IVLVGGGPSH LYLLKEWARE PEKGVRLTLI SAETDSPCRR
LLPGLLAGVY TRDQSHVDLL QLCQVSRGRF VRASVLGVDR EKKLLFCDDG RPPLRYDVLS
IDTESGLSVP ASITFSAPSA AREAESSPSV SASPAEGTSL GELEAAQVAS LDVGDQCMRA
CITPLRPLSQ FYSRWEAALQ RLANAALRVW ARSAFVPGAA EAHACAQADG AAPAEKANAK
LAGRAEDGVP EVFSVAVVGG GRDSVEICFA VKAAVEKKLA ELRAHWRTLR REGRATKDNE
TAPRQRDAQP QEAEAARGQK RESEDLGRLF RVEFHIFTET ASVLPRACSG TQTRVSRLLK
ASGIVVHPHW NVASVHVETA PPRSSFEASK DSSGLAGGSP LAAAAVEAAQ EGKGAERAAA
CAEFARRETS VRDATCGSDG RGETESEAAS CRKRLVGADG RHFEFDECVW CTPATPQPWF
QNAGLELTSN GFLAVDAFLR SLNTPNVFAV GDVAQVVGTP SPMDGDHAGE PLSKNLRLFL
RNGDGARLHR WHPVARLLSF VSCGMDYAVG TKGHLSFEGT WVSKLKTRMD INWIQKYQVL
PSGLTCPSLL SRKAPTPSAS PASPHADSAH GDVTRSSSAA LVAPELAAGE RKRGFCESLF
KRKEDEELSL GCRVLMGYVQ GRAGGRDKKG GASGCQNGGG TRCGGCGAKV PSTVLRRTMQ
ELEQANDLEA SQHRLLCQQR DASRARATRN SVEKGSASDG GAPARATKQL AAEAASRAAT
AGSGAPALQL AEALQLAALQ KRIDKEGRFY PLLFNREEVL VGLEDADDGC IFAARPLASL
TPRDAEKEAE SDDGRPTGRM TTFAEDPCDA PGDDNPLLVQ TVDFYRAFFD DAYVLGRIAA
THAMSDCYAM GAEPLVALLT AVVPYSTDCI MANNLLQLLG GCCSALSRDR CQLAGGHSAQ
GREMAAGLTV TGRLSRLRRS ERNGQTRSEG EAAEGNHRAP AGNLPIGYLP KGSAEAQEGD
VLILTKPLGT GVIMAGHVEG KSRGRWVYGA LDLMQVSNRA AAEILMDCGA TACTDVTGFG
LLGHLLEMLR ACRKSRIMAA VAGAEKTTLD TTSSDAEGSS CASSGGTADS SSGDFLPLVC
ARVLLPSLRL LDGAMTLMDQ GIHSSLLASN ARFFSALSLK TVGATPAAAE ATGDLPVQPL
SPSDLPPKLP ILFDPQTSGG LLAFVPASKA DECIKRLREE GGYDNAVVIG SVFERKTFVP
FPQKDASQGT RPRYAPWENV SGVVECLY
//
