ID F0VRP2_NEOCL Unreviewed; 883 AA.
AC F0VRP2;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Methyltransferase-like protein, related {ECO:0000313|EMBL:CBZ56390.1};
GN ORFNames=NCLIV_068140 {ECO:0000313|EMBL:CBZ56390.1};
OS Neospora caninum (strain Liverpool).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Neospora.
OX NCBI_TaxID=572307 {ECO:0000313|EMBL:CBZ56390.1, ECO:0000313|Proteomes:UP000007494};
RN [1] {ECO:0000313|Proteomes:UP000007494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|Proteomes:UP000007494};
RX PubMed=22457617; DOI=10.1371/journal.ppat.1002567;
RA Reid A.J., Vermont S.J., Cotton J.A., Harris D., Hill-Cawthorne G.A.,
RA Konen-Waisman S., Latham S.M., Mourier T., Norton R., Quail M.A.,
RA Sanders M., Shanmugam D., Sohal A., Wasmuth J.D., Brunk B., Grigg M.E.,
RA Howard J.C., Parkinson J., Roos D.S., Trees A.J., Berriman M., Pain A.,
RA Wastling J.M.;
RT "Comparative genomics of the apicomplexan parasites Toxoplasma gondii and
RT Neospora caninum: Coccidia differing in host range and transmission
RT strategy.";
RL PLoS Pathog. 8:e1002567-e1002567(2012).
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DR EMBL; FR823393; CBZ56390.1; -; Genomic_DNA.
DR RefSeq; XP_003886415.1; XM_003886366.1.
DR AlphaFoldDB; F0VRP2; -.
DR GeneID; 13445613; -.
DR VEuPathDB; ToxoDB:NCLIV_068140; -.
DR eggNOG; KOG1808; Eukaryota.
DR eggNOG; KOG2671; Eukaryota.
DR InParanoid; F0VRP2; -.
DR OrthoDB; 5488599at2759; -.
DR Proteomes; UP000007494; Chromosome XII.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR PANTHER; PTHR13370:SF3; TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG; 1.
DR Pfam; PF01170; UPF0020; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:CBZ56390.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007494};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022555};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CBZ56390.1};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555}.
FT DOMAIN 641..692
FT /note="UPF0020"
FT /evidence="ECO:0000259|Pfam:PF01170"
FT REGION 1..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 248..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 359..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 754..786
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..46
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..67
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 76..206
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 250..277
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..407
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 762..776
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 883 AA; 99029 MW; 842A7A4FE7CD33F9 CRC64;
MAANAPGEPR GASRRENTKG RKNASKSRED DGVKTMEWGR NKGAQGRKDK DKKKRKKKRK
KKRKRKRKKE EEKEEEKEEE KEEEKEEEEE EEEEEEEEEE EEEEEEEEEE EEEEEEEEEE
EEEEEEEEEE EKEEEEEEEE EEKEEEEEEE EEEEEEEEEE EEEEEEEEEE EEEEEEEEEE
EEEEEEEEEE EEEEEKEEEE EKKEEEEEEG RLCSGCALTQ VPPQIHFFLL VGHPLFPFFL
AAVPQHPSTM ASLQPPPPAA SSSPSFSPAP FPDSMPSPSP AGHIKLSSPA RSQPLRLLCW
FLCHNDYGDF RFEELEALAE EEGISREELW RGETAFASPV NPKPASSRSA PKLIVSQPPV
SALLSPSSSP SPPPPSLCSS PSSPPSPPFP PLPAPPPPSP AAAPFPPDSV SPLQTSNLSP
SPCVLPRFPS SAPSPPASPP LPVPPPSPCS SPSFSCMSPS FSCVSPSPGL GPHSASPVTP
PCAKASGAHF AYCYLPSEAV AERILKKSIL IRAFIEVWAE EQTYPEVLSR MQEPGNVLLF
RRYINDERTW AFRVKAFGKS LSVEEQREKM NFFSTLFKGT EKVSLDNPDI TLAVAEEWVH
ATEPGARPAE KPLRIFFGRE IASRHADKNA QPWWWPLRLS RRPVLGPTSL DVELAFLMCH
QAHIKRGSLV LDPFVGTGSI LISASYYGAT CIGSDIDIRV LKGYSVAYLN PHLNHPPGAK
KDVFRNFKEY GLARPEIVRG DNAAWVWRLP PPAGAEKSAR AAGGTSDKRE ESAPDSPDPP
AETDTQGRMR AYLQRSALGG GKPWVDAIVT DPPYGIRAGA RQSGHQQKHK RVAERSNEER
LTYISPTILY APQTVVSDLL NLAARLLVDN GRLVFLLPVD LST
//
