ID F0Y604_AURAN Unreviewed; 862 AA.
AC F0Y604;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=C2H2-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AURANDRAFT_63253 {ECO:0000313|EMBL:EGB09704.1};
OS Aureococcus anophagefferens (Harmful bloom alga).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Pelagophyceae; Pelagomonadales;
OC Aureococcus.
OX NCBI_TaxID=44056 {ECO:0000313|Proteomes:UP000002729};
RN [1] {ECO:0000313|EMBL:EGB09704.1, ECO:0000313|Proteomes:UP000002729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP 1984 {ECO:0000313|Proteomes:UP000002729};
RX PubMed=21368207; DOI=10.1073/pnas.1016106108;
RA Gobler C.J., Berry D.L., Dyhrman S.T., Wilhelm S.W., Salamov A.,
RA Lobanov A.V., Zhang Y., Collier J.L., Wurch L.L., Kustka A.B., Dill B.D.,
RA Shah M., VerBerkmoes N.C., Kuo A., Terry A., Pangilinan J., Lindquist E.A.,
RA Lucas S., Paulsen I.T., Hattenrath-Lehmann T.K., Talmage S.C., Walker E.A.,
RA Koch F., Burson A.M., Marcoval M.A., Tang Y.Z., Lecleir G.R., Coyne K.J.,
RA Berg G.M., Bertrand E.M., Saito M.A., Gladyshev V.N., Grigoriev I.V.;
RT "Niche of harmful alga Aureococcus anophagefferens revealed through
RT ecogenomics.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:4352-4357(2011).
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DR EMBL; GL833125; EGB09704.1; -; Genomic_DNA.
DR RefSeq; XP_009035748.1; XM_009037500.1.
DR AlphaFoldDB; F0Y604; -.
DR EnsemblProtists; EGB09704; EGB09704; AURANDRAFT_63253.
DR GeneID; 20224252; -.
DR KEGG; aaf:AURANDRAFT_63253; -.
DR eggNOG; ENOG502RZDN; Eukaryota.
DR InParanoid; F0Y604; -.
DR OrthoDB; 38685at2759; -.
DR Proteomes; UP000002729; Unassembled WGS sequence.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR Gene3D; 3.60.130.30; -; 1.
DR Gene3D; 3.30.70.660; Pseudouridine synthase I, catalytic domain, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR006342; FkbM_mtfrase.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR020097; PsdUridine_synth_TruA_a/b_dom.
DR InterPro; IPR020095; PsdUridine_synth_TruA_C.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR01444; fkbM_fam; 1.
DR PANTHER; PTHR34203:SF13; EXPRESSED PROTEIN; 1.
DR PANTHER; PTHR34203; METHYLTRANSFERASE, FKBM FAMILY PROTEIN; 1.
DR Pfam; PF05050; Methyltransf_21; 1.
DR Pfam; PF01416; PseudoU_synth_1; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002729};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..862
FT /note="C2H2-type domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003260752"
FT DOMAIN 311..353
FT /note="Pseudouridine synthase I TruA alpha/beta"
FT /evidence="ECO:0000259|Pfam:PF01416"
FT DOMAIN 677..832
FT /note="Methyltransferase FkbM"
FT /evidence="ECO:0000259|Pfam:PF05050"
FT REGION 22..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 862 AA; 91101 MW; 8B79F955031A04EA CRC64;
MHLQLPLVLL AARVAALHAP PSALTSPRCT ARRASAQPVA SKPSKDPSTA PPGAHRCRWC
GGTFVSRNAV FRHLREAESC RASATAEDAR AREAIFARAR DFTTTLLVGY VDASGADAER
LVAAATGASR TTRASSSKAR GRSAALESEL RAASRDVISI TAPAPVASTA DLNARLPPNV
RVLDRADGER VHAEASATQR AYHYLVPLSW LGVERAGGLV GEEIGASRGK FGALGTAHVS
RSDGGLPEDV RAALQGLKAA LKEATRTKGA WHNFADPSLD GGLLSPFSAA TRTRLHRCRA
AELVEVDGAT FARARVVVEV RGRGFLRQQV RRVVAVAVLA ARGALPADAF EVLTRRDVVL
PTPLPPDLAY FAGARYDFVE KRGAGDLFAG GGATDAWQRD LRSAVAARSS AAWLRDFEAG
EGPALRAELA ALARDGLDAV VAAESDADFL DAADLSPAPA VYGDALAELR RASDSGRWPK
TSLARSKLIK PGDDAASFTL SRGGGGSRAD ALFPALADAV FALEEAIAPG RPPSTRCAVN
RRAAFAPHVD SGEGHGQSTS LIVGLGDFSG GELAVERRVS DVRYAPLEFD GWRERHWTLP
FKGERYSLVF FTPAAPRARR SADDAAAAVL AGRASFAYRP GSSDALAIVE VLGDGCYATP
PPSLDFDFSP AGRTVLDGGA HVGAFSRYAL DEGAKRVVAF EPEPSNAALF RENNPGAELV
EAALVDGASG RATLVLGADQ RGERNTWRHA LDGLSHYVDA TERVGVDAVS FDEALDGVDF
VKLDVEGAEM AILAADREWR GVERLVFEWS FTKNPALAPF LVAVRRLEAA GFAVAYDGMG
TWDAGPTWPG RTDALVFCAR DI
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