ID F0YIA3_AURAN Unreviewed; 494 AA.
AC F0YIA3;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE RecName: Full=HECT domain-containing protein {ECO:0000259|PROSITE:PS50237};
GN ORFNames=AURANDRAFT_54835 {ECO:0000313|EMBL:EGB05194.1};
OS Aureococcus anophagefferens (Harmful bloom alga).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Pelagophyceae; Pelagomonadales;
OC Aureococcus.
OX NCBI_TaxID=44056 {ECO:0000313|Proteomes:UP000002729};
RN [1] {ECO:0000313|EMBL:EGB05194.1, ECO:0000313|Proteomes:UP000002729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP 1984 {ECO:0000313|Proteomes:UP000002729};
RX PubMed=21368207; DOI=10.1073/pnas.1016106108;
RA Gobler C.J., Berry D.L., Dyhrman S.T., Wilhelm S.W., Salamov A.,
RA Lobanov A.V., Zhang Y., Collier J.L., Wurch L.L., Kustka A.B., Dill B.D.,
RA Shah M., VerBerkmoes N.C., Kuo A., Terry A., Pangilinan J., Lindquist E.A.,
RA Lucas S., Paulsen I.T., Hattenrath-Lehmann T.K., Talmage S.C., Walker E.A.,
RA Koch F., Burson A.M., Marcoval M.A., Tang Y.Z., Lecleir G.R., Coyne K.J.,
RA Berg G.M., Bertrand E.M., Saito M.A., Gladyshev V.N., Grigoriev I.V.;
RT "Niche of harmful alga Aureococcus anophagefferens revealed through
RT ecogenomics.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:4352-4357(2011).
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DR EMBL; GL833143; EGB05194.1; -; Genomic_DNA.
DR RefSeq; XP_009040095.1; XM_009041847.1.
DR AlphaFoldDB; F0YIA3; -.
DR EnsemblProtists; EGB05194; EGB05194; AURANDRAFT_54835.
DR GeneID; 20222439; -.
DR KEGG; aaf:AURANDRAFT_54835; -.
DR eggNOG; KOG1426; Eukaryota.
DR InParanoid; F0YIA3; -.
DR OMA; WENKDAY; -.
DR OrthoDB; 8391at2759; -.
DR Proteomes; UP000002729; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR InterPro; IPR042469; HECTD3.
DR PANTHER; PTHR46654; E3 UBIQUITIN-PROTEIN LIGASE HECTD3; 1.
DR PANTHER; PTHR46654:SF1; E3 UBIQUITIN-PROTEIN LIGASE HECTD3; 1.
DR Pfam; PF00632; HECT; 1.
DR SMART; SM00119; HECTc; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS50237; HECT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002729};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT DOMAIN 118..486
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
FT ACT_SITE 450
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00104"
SQ SEQUENCE 494 AA; 56251 MW; D95F370937BFE782 CRC64;
MHASNLGNQR FTKSWITGGL CEIKYPSLVL SLSRNYIFAF TKKNIFNQYI RYTTAQAKKA
EDDYDYPDDL PLVVLNRRKA LVDPMAAPEL RLSSSVFGQL FDELHFLEAP LLRMGYMHPM
DDGQERTFKV KFDGEGVDDY GGPYREVFAQ IPSELQAFKC SPDSSRTTCY LPVFQPTPNT
ASDTELDVPK FILRPQYTAP MYLELCNFLG QLVGIALRSK ALMPLEFPPI IWKVLVGEDA
NAHDLASFDR DALMMLKRIS DIYEAWCKDD IRPRETPADP SAGFFWVSNL SDGTSVELHP
SGSSELVNMS DIPLFLKVSS ECRLQESKFA MLAMRTGLSC VIPPCVLQLL SWAELEKKVC
GTPGIDIELL KQNTEYDDDI QPNDNHITLF WDALRSFTGH ERSIFLRFVW ARTRLPPTQM
EFTQKFKIQA AIGDGPRESP NKYLPKAHTC FFSLNLPKYS SHEVMVSKLR YAMFNCIEMD
ADFKLTDTEL AAWS
//
