ID F0Z414_9CLOT Unreviewed; 596 AA.
AC F0Z414;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE SubName: Full=Putative two-component sensor kinase YesM {ECO:0000313|EMBL:EGB91127.1};
GN ORFNames=HMPREF0240_03862 {ECO:0000313|EMBL:EGB91127.1};
OS Clostridium sp. D5.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=556261 {ECO:0000313|EMBL:EGB91127.1, ECO:0000313|Proteomes:UP000003978};
RN [1] {ECO:0000313|EMBL:EGB91127.1, ECO:0000313|Proteomes:UP000003978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D5 {ECO:0000313|EMBL:EGB91127.1,
RC ECO:0000313|Proteomes:UP000003978};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Earl A., Feldgarden M., Gevers D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Borenstein D., Chapman S.B., Chen Z., Engels R.,
RA Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA Heiman D.I., Hepburn T.A., Howarth C., Jen D., Larson L., Mehta T.,
RA Park D., Pearson M., Richards J., Roberts A., Saif S., Shea T.D.,
RA Shenoy N., Sisk P., Stolte C., Sykes S.N., Walk T., White J., Yandava C.,
RA Sibley C.D., White A.P., Crowley S., Surette M.G., Strauss J.C.,
RA Ambrose C.E., Allen-Vercoe E., Haas B., Nusbaum C., Birren B.;
RT "The Genome Sequence of Clostridium sp. D5.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL870819; EGB91127.1; -; Genomic_DNA.
DR RefSeq; WP_009005142.1; NZ_GL870819.1.
DR AlphaFoldDB; F0Z414; -.
DR eggNOG; COG2972; Bacteria.
DR HOGENOM; CLU_020473_6_0_9; -.
DR OrthoDB; 9809348at2; -.
DR Proteomes; UP000003978; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EGB91127.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000003978};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 320..372
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
SQ SEQUENCE 596 AA; 67650 MW; 9CFFAC0C899AEED5 CRC64;
MKIGRKKYQR LSVKVVLIIL GITLVVSNIS GIVLYRYFSN VMMNQMKKDN QVTVNQLSSE
IDNIYEEAQK YGQQILINKS VQEYFSEDAP DSVVEAFKQK NEILDYINQV IMLSEHISSI
ALVKGEEEMM WSYVPFWDKI SMELCQEWYE QMSSAAADAG KPGDDGRYTV SRPYTFSYSR
TGGQSGQSLI SICIPSYSSR HVSERWGSLI INIDTQTIDE IIQRHSANFD ALGYFNNDKE
MVYVNDSTLD EKIFDQPGTK NDKERFPLKL QQETKMGGSI TAVLGDPGLF DSQRTDVQIL
LLVLLGGVFL IAAILIPLML RLMHPVSVLT NAMKKVGEGD LETQVDIHTR DEFETLGKDF
NQMVVRLNAS VQASLQHEKD KHDLEYEVLV AQINPHFIYN TLNTIIYLAK KEQGGDVVKI
TKALIDLLQD GIKLSDNKNY STVEEELWII GNYICIQNYR YKNMFKMIVD CSEELKKEHV
PTSVIQPLVE NALFHGIVPL GHPGRIWLTL RREVRNESGY IRICVSDEGV GVSEEKVRAI
MDGSMRLTDV SRNHIGVQNI IKRLTLLYGD EYQLSIRARE GGGTQVEVLI PLGTNQ
//
