ID F0ZA00_DICPU Unreviewed; 853 AA.
AC F0ZA00;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Glycogen [starch] synthase {ECO:0000256|RuleBase:RU363104};
DE EC=2.4.1.11 {ECO:0000256|RuleBase:RU363104};
GN ORFNames=DICPUDRAFT_148003 {ECO:0000313|EMBL:EGC39239.1};
OS Dictyostelium purpureum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=5786 {ECO:0000313|EMBL:EGC39239.1, ECO:0000313|Proteomes:UP000001064};
RN [1] {ECO:0000313|Proteomes:UP000001064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QSDP1 {ECO:0000313|Proteomes:UP000001064};
RX PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., Dalin E.,
RA Tu H., Huang E., Barry K., Lindquist E., Shapiro H., Bruce D., Schmutz J.,
RA Salamov A., Fey P., Gaudet P., Anjard C., Babu M.M., Basu S.,
RA Bushmanova Y., van der Wel H., Katoh-Kurasawa M., Dinh C., Coutinho P.M.,
RA Saito T., Elias M., Schaap P., Kay R.R., Henrissat B., Eichinger L.,
RA Rivero F., Putnam N.H., West C.M., Loomis W.F., Chisholm R.L., Shaulsky G.,
RA Strassmann J.E., Queller D.C., Kuspa A., Grigoriev I.V.;
RT "Comparative genomics of the social amoebae Dictyostelium discoideum and
RT Dictyostelium purpureum.";
RL Genome Biol. 12:R20.1-R20.23(2011).
CC -!- FUNCTION: Transfers the glycosyl residue from UDP-Glc to the non-
CC reducing end of alpha-1,4-glucan. {ECO:0000256|RuleBase:RU363104}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + H(+) + UDP; Xref=Rhea:RHEA:18549, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:58223, ChEBI:CHEBI:58885; EC=2.4.1.11;
CC Evidence={ECO:0000256|ARBA:ARBA00043769};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:18550;
CC Evidence={ECO:0000256|ARBA:ARBA00043769};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004964, ECO:0000256|RuleBase:RU363104}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 3 family.
CC {ECO:0000256|ARBA:ARBA00010686, ECO:0000256|RuleBase:RU363104}.
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DR EMBL; GL870961; EGC39239.1; -; Genomic_DNA.
DR RefSeq; XP_003284266.1; XM_003284218.1.
DR AlphaFoldDB; F0ZA00; -.
DR STRING; 5786.F0ZA00; -.
DR EnsemblProtists; EGC39239; EGC39239; DICPUDRAFT_148003.
DR GeneID; 10510170; -.
DR KEGG; dpp:DICPUDRAFT_148003; -.
DR eggNOG; KOG3742; Eukaryota.
DR InParanoid; F0ZA00; -.
DR OMA; RDVRNHI; -.
DR OrthoDB; 9432at2759; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000001064; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IBA:GO_Central.
DR GO; GO:0000045; P:autophagosome assembly; IEA:EnsemblProtists.
DR GO; GO:0005978; P:glycogen biosynthetic process; IBA:GO_Central.
DR GO; GO:0031288; P:sorocarp morphogenesis; IEA:EnsemblProtists.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR008631; Glycogen_synth.
DR PANTHER; PTHR10176:SF3; GLYCOGEN [STARCH] SYNTHASE; 1.
DR PANTHER; PTHR10176; GLYCOGEN SYNTHASE; 1.
DR Pfam; PF05693; Glycogen_syn; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 2.
PE 3: Inferred from homology;
KW Glycogen biosynthesis {ECO:0000256|ARBA:ARBA00023056,
KW ECO:0000256|RuleBase:RU363104};
KW Glycosyltransferase {ECO:0000256|RuleBase:RU363104};
KW Reference proteome {ECO:0000313|Proteomes:UP000001064};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363104}.
FT REGION 641..666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 685..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 724..853
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 652..666
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 853 AA; 95435 MW; C8152CB53B0AEFF4 CRC64;
MIFGTPNSTF LESKLHSSQG MTFSSMASGS GSGGLLHSSS GSSITEEVSL PPSNTVLFDI
SWEVAKKVGG IYTVLKSKAP VTVEEYKSRY ALIGPYNSET APTEFEPLVP GPLSSPIIEN
MMKKYGIQVH FGKWLVEGYP KVFLIDLPSS SHKLGEWRWD LMSGFEQPGD HETNESIVFG
YQSALLLKEF AEANPNDKYI AHFHEWQASV GLILLKKWKI PVSTIFTTHA TLLGRYLAAG
GVDLYNQIQN LNIDYEASKR GIYHRHWIEK KSANDAHVFT TVSEITAYES ESILSRKADV
ILPNGLKLDK FTALHEFQNL HAKYKNVLHE FVRGHFYGHY DFDLDNTLYV FTAGRSEYFN
KGVDMFLDAL AGLNKLLQQS GSTMTIVAFI IMPSKTNNFN IDTLKGQSHN RDLRRTCNSI
VESMGERLFE ATSRGRIISP EELLTQEDLV FLKRRIFALK QRPSLPPIVT HNMMDDVNDP
ILNHLRKIKL FNSKEDRVKI IYHPEFLNST NPLIPLDYTE FVRGCHLGIF VSYYEPWGYT
PAECTVLGVP SITSNLTGFA NYMSRGLNEP ESKGIFIVDR RFKSPNESVE QVTQYLWKFC
QMDRRQRIEL RNRTEKLSEL LDWKTLGKFY RSARSLAIER AFPPSKPISR SPSPSPTSNT
LKNSTSIQQL QQQLKQQVEQ QQKEQQQQQQ QQQTIPINIG KGETSQLSPN TMSSLLSDSL
NISNKKSSSL SGGAKFAEST INPTPNNTPS IITTSVGSSS KPPLPTTTTA TVSNTPTNTP
TIATVSSASV NTTKNSFQPS SQKSSSVNPI EQLTKLNSPT DRDFKNPLNE SGDGTSPSKA
KSKSIPIPSN KFK
//
