ID F0ZLK4_DICPU Unreviewed; 405 AA.
AC F0ZLK4;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Peptidase A1 domain-containing protein {ECO:0000259|PROSITE:PS51767};
GN ORFNames=DICPUDRAFT_79102 {ECO:0000313|EMBL:EGC35168.1};
OS Dictyostelium purpureum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=5786 {ECO:0000313|EMBL:EGC35168.1, ECO:0000313|Proteomes:UP000001064};
RN [1] {ECO:0000313|Proteomes:UP000001064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QSDP1 {ECO:0000313|Proteomes:UP000001064};
RX PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., Dalin E.,
RA Tu H., Huang E., Barry K., Lindquist E., Shapiro H., Bruce D., Schmutz J.,
RA Salamov A., Fey P., Gaudet P., Anjard C., Babu M.M., Basu S.,
RA Bushmanova Y., van der Wel H., Katoh-Kurasawa M., Dinh C., Coutinho P.M.,
RA Saito T., Elias M., Schaap P., Kay R.R., Henrissat B., Eichinger L.,
RA Rivero F., Putnam N.H., West C.M., Loomis W.F., Chisholm R.L., Shaulsky G.,
RA Strassmann J.E., Queller D.C., Kuspa A., Grigoriev I.V.;
RT "Comparative genomics of the social amoebae Dictyostelium discoideum and
RT Dictyostelium purpureum.";
RL Genome Biol. 12:R20.1-R20.23(2011).
CC -!- SIMILARITY: Belongs to the peptidase A1 family.
CC {ECO:0000256|ARBA:ARBA00007447}.
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DR EMBL; GL871069; EGC35168.1; -; Genomic_DNA.
DR RefSeq; XP_003288306.1; XM_003288258.1.
DR AlphaFoldDB; F0ZLK4; -.
DR STRING; 5786.F0ZLK4; -.
DR EnsemblProtists; EGC35168; EGC35168; DICPUDRAFT_79102.
DR GeneID; 10501724; -.
DR KEGG; dpp:DICPUDRAFT_79102; -.
DR eggNOG; KOG1339; Eukaryota.
DR InParanoid; F0ZLK4; -.
DR OMA; KKPVQYT; -.
DR OrthoDB; 335768at2759; -.
DR Proteomes; UP000001064; Unassembled WGS sequence.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd05471; pepsin_like; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 2.
DR InterPro; IPR001461; Aspartic_peptidase_A1.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR034164; Pepsin-like_dom.
DR InterPro; IPR033121; PEPTIDASE_A1.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR PANTHER; PTHR47965; ASPARTYL PROTEASE-RELATED; 1.
DR PANTHER; PTHR47965:SF12; PEPTIDASE A1 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00026; Asp; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 2.
DR PROSITE; PS51767; PEPTIDASE_A1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001064};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..405
FT /note="Peptidase A1 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003265222"
FT DOMAIN 72..405
FT /note="Peptidase A1"
FT /evidence="ECO:0000259|PROSITE:PS51767"
FT ACT_SITE 88
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
FT ACT_SITE 293
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
SQ SEQUENCE 405 AA; 45970 MW; 28A2E420C7311A28 CRC64;
MKSILLLSIF LIFVFNNEYA NANRNSLKLP IYTKQASNHI NNNFNDLASN KRMVSTKERN
VPIKLEGDII QLLIDVNVGG IKQQVVVDTG SNYLVVPSVY CRNCEQQRPY YQPSKYATFM
KCNDECSIMG NSCTNVQTLA GIELFCSYQE SYVQGTEILN LLVQDTFSFN NYTENVMATF
GIIVTTQGHT LRNGVLGLGK TCRGCRKSPT ASILENLNLS NSFSLSFNEN FQGTLVLGDA
DPSDFDKNLT FTEMLTIDDS HYGVPIKSII VNDRYSPNYM LIPPEYFGDF ILDSGATMTS
LNEPAYNLIA KFLQRDCNPG MCHENNFFNG YCFDFPDEYF NTFPIINIEM EGGASMKIEP
KNYIFSNYVN GIKYHCLDHY VHFDNENEKI GIAKRPYGYS YNNNF
//
