ID   F0ZNB9_DICPU            Unreviewed;       850 AA.
AC   F0ZNB9;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   RecName: Full=CNH domain-containing protein {ECO:0000259|PROSITE:PS50219};
GN   ORFNames=DICPUDRAFT_153214 {ECO:0000313|EMBL:EGC34554.1};
OS   Dictyostelium purpureum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=5786 {ECO:0000313|EMBL:EGC34554.1, ECO:0000313|Proteomes:UP000001064};
RN   [1] {ECO:0000313|Proteomes:UP000001064}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=QSDP1 {ECO:0000313|Proteomes:UP000001064};
RX   PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., Dalin E.,
RA   Tu H., Huang E., Barry K., Lindquist E., Shapiro H., Bruce D., Schmutz J.,
RA   Salamov A., Fey P., Gaudet P., Anjard C., Babu M.M., Basu S.,
RA   Bushmanova Y., van der Wel H., Katoh-Kurasawa M., Dinh C., Coutinho P.M.,
RA   Saito T., Elias M., Schaap P., Kay R.R., Henrissat B., Eichinger L.,
RA   Rivero F., Putnam N.H., West C.M., Loomis W.F., Chisholm R.L., Shaulsky G.,
RA   Strassmann J.E., Queller D.C., Kuspa A., Grigoriev I.V.;
RT   "Comparative genomics of the social amoebae Dictyostelium discoideum and
RT   Dictyostelium purpureum.";
RL   Genome Biol. 12:R20.1-R20.23(2011).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GL871093; EGC34554.1; -; Genomic_DNA.
DR   RefSeq; XP_003288930.1; XM_003288882.1.
DR   AlphaFoldDB; F0ZNB9; -.
DR   STRING; 5786.F0ZNB9; -.
DR   EnsemblProtists; EGC34554; EGC34554; DICPUDRAFT_153214.
DR   GeneID; 10499594; -.
DR   KEGG; dpp:DICPUDRAFT_153214; -.
DR   eggNOG; KOG2063; Eukaryota.
DR   InParanoid; F0ZNB9; -.
DR   OMA; DETEMAR; -.
DR   OrthoDB; 38195at2759; -.
DR   Proteomes; UP000001064; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0006914; P:autophagy; IBA:GO_Central.
DR   GO; GO:0034058; P:endosomal vesicle fusion; IBA:GO_Central.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR   InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR   InterPro; IPR001180; CNH_dom.
DR   InterPro; IPR032914; Vam6/VPS39/TRAP1.
DR   InterPro; IPR019452; VPS39/TGF_beta_rcpt-assoc_1.
DR   InterPro; IPR019453; VPS39/TGF_beta_rcpt-assoc_2.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR12894; CNH DOMAIN CONTAINING; 1.
DR   PANTHER; PTHR12894:SF33; TETRATRICOPEPTIDE-LIKE HELICAL DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00780; CNH; 1.
DR   Pfam; PF10366; Vps39_1; 1.
DR   Pfam; PF10367; Vps39_2; 1.
DR   SMART; SM00036; CNH; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50236; CHCR; 1.
DR   PROSITE; PS50219; CNH; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001064}.
FT   DOMAIN          19..290
FT                   /note="CNH"
FT                   /evidence="ECO:0000259|PROSITE:PS50219"
SQ   SEQUENCE   850 AA;  97578 MW;  8D63562A58D4B9C1 CRC64;
     MNRVDMNAFV SQSILDKLTQ RIECIDSWEC KGEKFLVIGT TEGYLLTYFV YETKDHNGNI
     QVSVKIRETR QISKKPISQI TVFDDFNKIV TLSDGDLRIH DLMSQVGESS LLQKARGCSA
     YAVSYQPGLS LSLVAAVKKK LVLYAWDGSD FYEQKEFNMP DLAKNIDYRG NYIVVCFKKA
     YNIINTSDGS VTNVDADKLT FTTFLQNNEF LMVRGNMSFF INTGGSPVRR HSMTWMDAPS
     SMVIYEPFAI AVEGRLIEIQ ILPDPNDPKT ISQSMFLQGC KSISAKKDIY VSSPSGVWRI
     LPHPILELVD QMVTKLEYET AINLLQTTQE NIPHLKERLI KIKTSAAYHL FQKEQFQTAM
     GYFISAQVDP LKIISLYPGL LPRHLQDKLS IPIHIRDIEN NPRALPELEH YLVEFRKNKI
     EYQSPPELLN SGYTLQELVD TTLLKVYIKH KPSLIPHFFH LKNHCHVEES ERVLLEEKKT
     TELILFYKSK DLHRKALTLL AKTNNNNPND TIAYLCHLGE KHINIILDNS KWVLQKSPNE
     ALAIFTTDRK EPLAPEEVIP HLRQYAPLLL RPYLEHIIND PVGPNKNPDY HNQLAFEYLG
     AITDQINIMK QQGTTRKPGA IPAGSEPAPL GPLRNRLIQF LQTSKCYLPE KMLSIFPIDD
     LFEERAILLS KIGRHEQALT IYAHKLKNYQ MAEEYCDRHY NKDSEESRDV YLSLLNVYLK
     PDGQSEPLLE PALELLNKHY RSINTPKALN LLPLNTPIEK LYPFFEAVIR DNTKTKRDNQ
     VVKNLFKSEN FKIKDELSQL RSGAIKITED LSCPICGKIF LGTQAFVAQP NGTAVHYHHK
     NDKQYQKYFE
//