ID F1AR04_PLAVI Unreviewed; 388 AA.
AC F1AR04;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Merozoite surface protein 1 {ECO:0000256|ARBA:ARBA00022062};
DE AltName: Full=Merozoite surface antigen {ECO:0000256|ARBA:ARBA00031689};
DE AltName: Full=PMMSA {ECO:0000256|ARBA:ARBA00032276};
DE Flags: Fragment;
GN Name=msp1 {ECO:0000313|EMBL:ADX86856.1};
OS Plasmodium vivax (malaria parasite P. vivax).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=5855 {ECO:0000313|EMBL:ADX86856.1};
RN [1] {ECO:0000313|EMBL:ADX86856.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SG {ECO:0000313|EMBL:ADX86856.1};
RX PubMed=21029478; DOI=10.1186/1475-2875-9-305;
RA Ng L.C., Lee K.S., Tan C.H., Ooi P.L., Lam-Phua S.G., Lin R., Pang S.C.,
RA Lai Y.L., Solhan S., Chan P.P., Wong K.Y., Ho S.T., Vythilingam I.;
RT "Entomologic and molecular investigation into Plasmodium vivax transmission
RT in Singapore, 2009.";
RL Malar. J. 9:305-305(2010).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004609};
CC Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}. Membrane
CC {ECO:0000256|ARBA:ARBA00004589}; Lipid-anchor, GPI-anchor
CC {ECO:0000256|ARBA:ARBA00004589}.
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DR EMBL; GU971667; ADX86856.1; -; Genomic_DNA.
DR AlphaFoldDB; F1AR04; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR010901; MSP1_C.
DR InterPro; IPR024730; MSP1_EGF_1.
DR Pfam; PF12946; EGF_MSP1_1; 1.
DR Pfam; PF07462; MSP1_C; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
PE 4: Predicted;
KW Merozoite {ECO:0000313|EMBL:ADX86856.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 1..242
FT /note="Merozoite surface 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07462"
FT DOMAIN 312..348
FT /note="Merozoite surface protein EGF"
FT /evidence="ECO:0000259|Pfam:PF12946"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADX86856.1"
FT NON_TER 388
FT /evidence="ECO:0000313|EMBL:ADX86856.1"
SQ SEQUENCE 388 AA; 43822 MW; F674FA93362C2FC7 CRC64;
IALPLFGNND DDGEEDQVTT GEAESEAPEI LVPAGISDYD VVYLKPLAGM YKTIKKQLEN
HVNAFNTNIT DMLDSRLKKR NYFLEVLNSD LNPFKYSSSG EYIIKDPYKL LDLEKKKKLI
GSYKYIGASI DMDLATANDG VTYYNKMGEL YKTHLDGVKT EIKKVEADIK AEDDKIKTIG
SDSTKTTEKT QSMAKKAELE KYLPFLNSLQ KEYESLVSKV NTYTDNLKKV ISNCQLEKKE
AEITVKKLQD YNKMDEKLEE YKKSEKKNEV KSSGLLEKLM KSKLIKENES KEILSQLLNV
QTQLLTMSSE HTCIDTNVPD NAACYRYLDG TEEWRCLLTF KEEGGKCVPA SNVTCKDNNG
GCAPEAECKM TDSNKIVCKC TKEGSEQL
//
