ID F1DI26_EPICO Unreviewed; 136 AA.
AC F1DI26;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 03-MAY-2023, entry version 33.
DE SubName: Full=TLR2 {ECO:0000313|EMBL:ADY38948.1};
DE Flags: Fragment;
OS Epinephelus coioides (Orange-spotted grouper) (Epinephelus nebulosus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Serranoidei; Serranidae; Epinephelinae;
OC Epinephelini; Epinephelus.
OX NCBI_TaxID=94232 {ECO:0000313|EMBL:ADY38948.1};
RN [1] {ECO:0000313|EMBL:ADY38948.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=21540114; DOI=10.1016/j.fsi.2011.04.012;
RA Li Y.W., Luo X.C., Dan X.M., Huang X.Z., Qiao W., Zhong Z.P., Li A.X.;
RT "Orange-spotted grouper (Epinephelus coioides) TLR2, MyD88 and IL-1beta
RT involved in anti-Cryptocaryon irritans response.";
RL Fish Shellfish Immunol. 30:1230-1240(2011).
RN [2] {ECO:0000313|EMBL:ADY38948.1}
RP NUCLEOTIDE SEQUENCE.
RA Li Y., Li A.;
RT "Molecular cloning and expression analysis of TLR2 gene in grouper,
RT Epinephelus coioides.";
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HQ851369; ADY38948.1; -; mRNA.
DR AlphaFoldDB; F1DI26; -.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR GO; GO:0002224; P:toll-like receptor signaling pathway; IEA:InterPro.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR017241; Toll-like_receptor.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR24365; TOLL-LIKE RECEPTOR; 1.
DR PANTHER; PTHR24365:SF17; TOLL-LIKE RECEPTOR 2; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR01537; INTRLKN1R1F.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 2: Evidence at transcript level;
FT DOMAIN 1..132
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADY38948.1"
FT NON_TER 136
FT /evidence="ECO:0000313|EMBL:ADY38948.1"
SQ SEQUENCE 136 AA; 16286 MW; 89C7FA1A2DDFBBA2 CRC64;
DSGWVVTYLV PELEQAEPPL QLCLHKRDFV PGGWILDNIM DAIEKSHRTL FVLSQHFIRS
EWCKYELDYT HFRLFDQNDD TVVLILLEPI DKDTIPKKFC KLRRVMNSRT YLEWPDDDGQ
IPRFWHSLRT AIKRPE
//
