ID F1KG71_9HIV1 Unreviewed; 225 AA.
AC F1KG71;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Pol protein {ECO:0000313|EMBL:ADY91236.1};
DE Flags: Fragment;
GN Name=pol {ECO:0000313|EMBL:ADY91236.1};
OS Human immunodeficiency virus 1.
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
OX NCBI_TaxID=11676 {ECO:0000313|EMBL:ADY91236.1};
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1] {ECO:0000313|EMBL:ADY91236.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=15clone35 {ECO:0000313|EMBL:ADY91236.1};
RX PubMed=21241214; DOI=10.1089/aid.2010.0346;
RA Persaud D., Bedri A., Ziemniak C., Moorthy A., Gudetta B., Abashawl A.,
RA Mengistu Y., Omer S.B., Isehak A., Kumbi S., Adamu R., Lulseged S.,
RA Ashworth R., Hassen E., Ruff And The Ethiopian Swen Study Team A.;
RT "Slower Clearance of Nevirapine Resistant Virus in Infants Failing Extended
RT Nevirapine Prophylaxis for Prevention of Mother-to-Child HIV
RT Transmission.";
RL AIDS Res. Hum. Retroviruses 27:823-829(2011).
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DR EMBL; JF334899; ADY91236.1; -; Genomic_DNA.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR41694; ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN; 1.
DR PANTHER; PTHR41694:SF3; RNA-DIRECTED DNA POLYMERASE-RELATED; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022918};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Viral release from host cell {ECO:0000256|ARBA:ARBA00023113};
KW Virion maturation {ECO:0000256|ARBA:ARBA00023113}.
FT DOMAIN 26..216
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADY91236.1"
FT NON_TER 225
FT /evidence="ECO:0000313|EMBL:ADY91236.1"
SQ SEQUENCE 225 AA; 26356 MW; 6FCA762620D9CE4E CRC64;
PKVKQWPLTE EKIKALTAIC EDMEKEGKIS KIGPENPYNT PVFAIKKKDS TKWRKLVDFR
ELNKRTQDFW EIQLGIPHPS GLKKKRSMTV LDVGDAYFSV PLDEGFRKYT AFTIPSINNE
TPGIRYQYNV PPQGWKGSPA IFQSSMTKIL EPFRTKNPEI VIYQYMDDLY VGSDLEIGPH
REKIEELREH LLKWGFTTPD KKRQKEPPFL WMGYELHPDK WTVQP
//
