ID F1KQ86_ASCSU Unreviewed; 1029 AA.
AC F1KQ86;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Myosin-XVIIIa {ECO:0000313|EMBL:ADY40040.1};
OS Ascaris suum (Pig roundworm) (Ascaris lumbricoides).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX NCBI_TaxID=6253 {ECO:0000313|EMBL:ADY40040.1};
RN [1] {ECO:0000313|EMBL:ADY40040.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=21685128; DOI=10.1101/gr.121426.111;
RA Wang J., Czech B., Crunk A., Wallace A., Mitreva M., Hannon G.J.,
RA Davis R.E.;
RT "Deep small RNA sequencing from the nematode Ascaris reveals conservation,
RT functional diversification, and novel developmental profiles.";
RL Genome Res. 21:1462-1477(2011).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; JI164116; ADY40040.1; -; mRNA.
DR AlphaFoldDB; F1KQ86; -.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01386; MYSc_Myo18; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 4.10.270.10; Myosin, subunit A; 1.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR036064; MYSc_Myo18.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF709; UNCONVENTIONAL MYOSIN-XV; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF17820; PDZ_6; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 2: Evidence at transcript level;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}.
FT DOMAIN 43..136
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 223..951
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT BINDING 316..323
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1029 AA; 114111 MW; 8C669504F57498ED CRC64;
MSSHNKETNS QNGSVTFQSF PVLKDLPKLS LPALAPVQVN QRTLTLHRNV AGDFGFNVRR
TQFPDFRGRL RAVVFAEPTE VRCGPPRPSD IRAGLLPGDQ LVKMNGRSVE SLGREELLAI
IQNSGDQVEL TVRAMPELAE LCDRTQRGVR DTGDSLMLPP VSNTYLDENI TEDERYWLMH
KNGYTMARMI ETQSDGKVHV MVAGAEMVVD VTDVDKANPS NMDRVEDLAR LRYINETSAV
HVLRHRYGSG LLYTNAGALS IICMANEQEP LLCNKLVALF KGCRRQQMPP HIYASAQQAY
RKMQMSGRSQ CLILTGVTGS GKSTQLRNVC HYLCEIAGWT KSLSYGKISA ALGVVEAFGN
CATRLSKNAT RFAQMFSLSF DAAASLRFAS IRTFLLDSSH VVKQANGEAN FHVFYYLLEG
AEPELVQSLR LDSITKPFRS PLIREEDKNA ALLGWSRLKE ALSTLGISAA HARAIFSLLA
AIGHLCCAGA TQSPAQKAQF VRASSAQHAA ALLSVGTDQL ASAVFRGKMS SGGQSGPGNV
MNRFSLSNRG QNGQEALEAF VAHLYNELFY AVVALLNRGL GATNLATTTS ITIIDFPGGN
FNAAWSEESQ RTSGLADLTY NYLNERIAEL FYDTSFTEPI ELYDREQVEV DIEKPTLCPH
QITRLIDQKQ QLLNCVDIDL RSEERRGLLH ILDEEALFPG ATDDSFFERI FVHLGESRLI
RRGCRPREFV LGHCLGGSPT VYSVNGWVKA AQPNVSEGSV LTLLHSSRDA AINELFSPFG
MTRSESATLN IRRATQAAKL DATGLPTACG FFSNISMQTE CIISFARHAG GVQFVHCMQP
QPPSEDDGRS TGSEMLLDVP FVRSQLRSLL IIDAARASSR GYPERLSFKD FRRRFQCLVK
SSSSLDDVLD DRAAAGRILE DTGVFPHTYR LGLSQVLLRS DVLADLENRR ELCLSGLIVS
FQRACRKHLS AKWLARRRTL DSAIRCIQRS GKCYIKVREW SWWRLYTKVT PLLAAARCFR
FSCLRFSTS
//
