ID F1LK02_MANZA Unreviewed; 416 AA.
AC F1LK02;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Xanthine dehydrogenase {ECO:0000313|EMBL:ABX45906.1};
DE Flags: Fragment;
GN Name=Xdh {ECO:0000313|EMBL:ABX45906.1};
OS Manilkara zapota (Sapodilla plum) (Achras zapota).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; Ericales; Sapotaceae; Sapotoideae; Manilkara.
OX NCBI_TaxID=3741 {ECO:0000313|EMBL:ABX45906.1};
RN [1] {ECO:0000313|EMBL:ABX45906.1}
RP NUCLEOTIDE SEQUENCE.
RA Morton C.M.;
RT "Newly Sequenced Nuclear Gene (Xdh) for Inferring Angiosperm Phylogeny.";
RL Ann. Mo. Bot. Gard. 98:63-89(2011).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- PATHWAY: Alkaloid biosynthesis. {ECO:0000256|ARBA:ARBA00004913}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; EU264333; ABX45906.1; -; Genomic_DNA.
DR AlphaFoldDB; F1LK02; -.
DR SMR; F1LK02; -.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0009820; P:alkaloid metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 1.10.150.120; [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.30.390.50; CO dehydrogenase flavoprotein, C-terminal domain; 1.
DR Gene3D; 3.30.43.10; Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2; 1.
DR InterPro; IPR002888; 2Fe-2S-bd.
DR InterPro; IPR036884; 2Fe-2S-bd_dom_sf.
DR InterPro; IPR016208; Ald_Oxase/xanthine_DH-like.
DR InterPro; IPR005107; CO_DH_flav_C.
DR InterPro; IPR036683; CO_DH_flav_C_dom_sf.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016167; FAD-bd_PCMH_sub1.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR002346; Mopterin_DH_FAD-bd.
DR PANTHER; PTHR45444:SF3; ALDEHYDE OXIDASE_XANTHINE DEHYDROGENASE, MOLYBDOPTERIN BINDING PROTEIN; 1.
DR PANTHER; PTHR45444; XANTHINE DEHYDROGENASE; 1.
DR Pfam; PF03450; CO_deh_flav_C; 1.
DR Pfam; PF00941; FAD_binding_5; 1.
DR Pfam; PF01799; Fer2_2; 1.
DR SMART; SM01092; CO_deh_flav_C; 1.
DR SUPFAM; SSF55447; CO dehydrogenase flavoprotein C-terminal domain-like; 1.
DR SUPFAM; SSF47741; CO dehydrogenase ISP C-domain like; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 4: Predicted;
KW Alkaloid metabolism {ECO:0000256|ARBA:ARBA00022589}.
FT DOMAIN 134..319
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABX45906.1"
FT NON_TER 416
FT /evidence="ECO:0000313|EMBL:ABX45906.1"
SQ SEQUENCE 416 AA; 46227 MW; 8E0B4F9AB9116DF5 CRC64;
GFIMSMYALL RSSQTPPTEE QIEESLAGNL CRCTGYRPII DAFRVFAKTN DMLYADASLN
GTLRGESICP STGKPCSCGL ETVTKEDTIE PKMTCQDRFG ATSYSEIDGL TYTNKELIFP
PELLLRKLTF LNLSGSGGLK WYRPLQLQHV LDLKARYPEA KLVVGNTEIG IEMRLKGFQY
QVLICVAHVS ELNKLTVKDN GLEIGAAVRL SELLKVFRKV TKEQVAHKTS SCMAFIEQIK
WFAGTQIKNV ASVGGNICTA SPISDLNPLW IAAGAKFQII DCKGNIRMAA AENFFLGYRK
VDLASNEILL SIFLPWTRPF EFVKEFKQAH RRDDDIAIVN AGMRVCFEEK NEKWIVSDAS
IVYGGVAPLS VSAAKTKNFL IAKTWNHELL QGALKVLEED ILLKEDAPGG MVEFSI
//
