ID F1LK49_BERLA Unreviewed; 403 AA.
AC F1LK49;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Xanthine dehydrogenase {ECO:0000313|EMBL:ABX45953.1};
DE Flags: Fragment;
GN Name=Xdh {ECO:0000313|EMBL:ABX45953.1};
OS Berzelia lanuginosa (Buttonbush).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Bruniales; Bruniaceae; Brunieae; Berzelia.
OX NCBI_TaxID=28530 {ECO:0000313|EMBL:ABX45953.1};
RN [1] {ECO:0000313|EMBL:ABX45953.1}
RP NUCLEOTIDE SEQUENCE.
RA Morton C.M.;
RT "Newly Sequenced Nuclear Gene (Xdh) for Inferring Angiosperm Phylogeny.";
RL Ann. Mo. Bot. Gard. 98:63-89(2011).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- PATHWAY: Alkaloid biosynthesis. {ECO:0000256|ARBA:ARBA00004913}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; EU264380; ABX45953.1; -; Genomic_DNA.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0009820; P:alkaloid metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 1.10.150.120; [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.30.390.50; CO dehydrogenase flavoprotein, C-terminal domain; 1.
DR Gene3D; 3.30.43.10; Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2; 1.
DR InterPro; IPR002888; 2Fe-2S-bd.
DR InterPro; IPR036884; 2Fe-2S-bd_dom_sf.
DR InterPro; IPR016208; Ald_Oxase/xanthine_DH-like.
DR InterPro; IPR005107; CO_DH_flav_C.
DR InterPro; IPR036683; CO_DH_flav_C_dom_sf.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016167; FAD-bd_PCMH_sub1.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR002346; Mopterin_DH_FAD-bd.
DR PANTHER; PTHR45444:SF3; ALDEHYDE OXIDASE_XANTHINE DEHYDROGENASE, MOLYBDOPTERIN BINDING PROTEIN; 1.
DR PANTHER; PTHR45444; XANTHINE DEHYDROGENASE; 1.
DR Pfam; PF03450; CO_deh_flav_C; 1.
DR Pfam; PF00941; FAD_binding_5; 1.
DR Pfam; PF01799; Fer2_2; 1.
DR SMART; SM01092; CO_deh_flav_C; 1.
DR SUPFAM; SSF55447; CO dehydrogenase flavoprotein C-terminal domain-like; 1.
DR SUPFAM; SSF47741; CO dehydrogenase ISP C-domain like; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 4: Predicted;
KW Alkaloid metabolism {ECO:0000256|ARBA:ARBA00022589}.
FT DOMAIN 124..309
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABX45953.1"
FT NON_TER 403
FT /evidence="ECO:0000313|EMBL:ABX45953.1"
SQ SEQUENCE 403 AA; 44559 MW; 995ACEAF2855259E CRC64;
RSSRTPPSEE QIEEXLAGNL CRCTGYRPIV DAFRVFAKTD DLLYTNRSLQ GSGRGEFVCP
STGKPCSCGS KTVSGDETIK QSSGCCNGNR PVSYSDIDGS AYTNKELIFP PELLLNKLTY
LNLSGSGGLK WYRPLRLQHV LDLKARYPAA KLVIGNTEVG IEMRLKRIQY PVLISVAHIP
ELNTLSVKDD GLEIGAAVRL SELLNVFKKV ITERASYETS SCRAFMEQIK WFAGTQIRNV
ASVGGNICTA SPISDLNPLW MAAGAKFQII DCKGNIRTTL AENFFLGYRK VDLASAEILL
SVFLPWTRTY EHVKEFKQAH RRDDDIAIVN AGMRVYLEDK DKKWVVSDAS IVYGGVAPLS
LSASRTKDFL IGKSWNKELL PGALKVLEHD ILLKEDAPGG MVE
//
