ID   F1MIW4_BOVIN            Unreviewed;      1630 AA.
AC   F1MIW4;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 3.
DT   27-MAR-2024, entry version 74.
DE   SubName: Full=Maestro heat like repeat family member 1 {ECO:0000313|Ensembl:ENSBTAP00000037251.5};
GN   Name=MROH1 {ECO:0000313|Ensembl:ENSBTAP00000037251.5,
GN   ECO:0000313|VGNC:VGNC:31609};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000037251.5, ECO:0000313|Proteomes:UP000009136};
RN   [1] {ECO:0000313|Ensembl:ENSBTAP00000037251.5, ECO:0000313|Proteomes:UP000009136}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000037251.5,
RC   ECO:0000313|Proteomes:UP000009136};
RA   Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA   Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA   Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT   "ARS-UCD1.2.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSBTAP00000037251.5}
RP   IDENTIFICATION.
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000037251.5};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_005215247.2; XM_005215190.3.
DR   Ensembl; ENSBTAT00000037418.5; ENSBTAP00000037251.5; ENSBTAG00000014458.6.
DR   GeneID; 515055; -.
DR   CTD; 727957; -.
DR   VEuPathDB; HostDB:ENSBTAG00000014458; -.
DR   VGNC; VGNC:31609; MROH1.
DR   GeneTree; ENSGT00940000156930; -.
DR   HOGENOM; CLU_003168_0_1_1; -.
DR   InParanoid; F1MIW4; -.
DR   OMA; EVYIKAM; -.
DR   TreeFam; TF315201; -.
DR   Proteomes; UP000009136; Chromosome 14.
DR   Bgee; ENSBTAG00000014458; Expressed in spermatocyte and 104 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR021133; HEAT_type_2.
DR   InterPro; IPR045206; Maestro_heat-like_prot.
DR   InterPro; IPR048465; Maestro_HEAT_rpt.
DR   PANTHER; PTHR23120:SF44; MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 1; 1.
DR   PANTHER; PTHR23120; MAESTRO-RELATED HEAT DOMAIN-CONTAINING; 1.
DR   Pfam; PF21047; Maestro_HEAT; 1.
DR   SUPFAM; SSF48371; ARM repeat; 2.
DR   PROSITE; PS50077; HEAT_REPEAT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT   REPEAT          1600..1630
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ   SEQUENCE   1630 AA;  179948 MW;  880FDDB5922E4E60 CRC64;
     MSETYAKRLS AILLDAVTDK DPQMQEQVCG ALCDFGESKP AEVLSACEEH LRLHEKLAHP
     YRTIILRAME IVVSNHISEL DKDTARAIIL LASNEMTKVK ELVSDWQQAA SSVLVAVGRR
     FISSVMEELL SKFQPGLLPH PCTVHTLASL SVSNVFGVVP FLTSILSTML PMLGAAKHDS
     MKVVFCCALQ RFSESILEYL ANLDQAPDPT VRKDAFASDI FGAYDILFHQ WLQSGGAKLR
     LAVVEALGPM SHLLPSEKLE EQLPKLLPRV LAFYKKHTET VHVSKSLGQI LEAAVSVGSR
     TLDIHLNSLL AALHAQICVP VESSSPLVMS NQKEVLRCFT VLACCSPDRL LAFLLPKLDT
     SNERTRVGTL QVLRHVINAA AAQMEVKKPV ILSSMKLPLL DTNNKVKRAV VQVVSAMAHH
     GYLEQPGGKA MVEYIVQQCA LPPEAEIQKL GADSEALAAD SVRAISVSTL YLVSTTVDRM
     GEVLWPYLLE FLVPIRFTRA LSPLCRSLVH LAQKRQEAGA HAPLIQYNGN VHLPSPYAIT
     TRLLAVSSHP YVGDGRGAAS LRLLNVLHQD IHPALGQRWV TAIPLLLEHL DEYSEETLSQ
     KEWEEKLLVF LRDSLAVVSD NTWVCHLTLE MCKQLPNYNG TPLEKNFLYK CVGTTLGAAS
     SKVVRKHLRE LLETARYQEE REHEGLACCF GICAISHLDD TLAQLDDFVK SDVLRKSAGI
     FNLFKNRSES EANKVRSALI LCYGHVAAGA PRELLLARVE ADLFWNMSEC FSTKDPALRL
     SLVQSVCMAT QAICSSAHSS SFHLSRKAEL VAQMVEFIRA EPPDSLKTPI WKKAMLACTY
     LVTLEPALEE QVQADLIHSC LHRVMAVLPE PEEGDSPQES LYLDTVQVLK DLLTSLLLWN
     MTPLGLQVML EHLSPWIKSP RGHERVRAVG LSACLLQFFL QHLQISALVP FHNLGLLIGL
     FSPRCADLWP ATRREAVSCI HSLLYLQLTC VGFSRDYQDD VAEQLLSLKD GLVHPDPAIL
     FHTCHSIAQL IAKRLPPDQL INLLLTLFES LGDPDKNCSR AASVMINCLL KERGNMLQEK
     VPEIVSVLRS KLQETQEEHI LQAAQHSVFA LATHHCASVV SNLLGSPLPF DSHTCTLWRA
     LALEPGLAAQ VLGLLLEKIS KDVLFEESQA FLLSSTPDRV ATLLPLAATC ALHEVASAPA
     SGPAVLELYP QLFVALLLRV SCTVGVQPPR QLQAKERRSA SSGLASRSLE PCSSAVDALQ
     AVLVRGGNED VVQCMELDGG WQLLRTSAGH EEGVTRLASA MAKFAGPRLP LVMKLLFTTQ
     SSMYEVQRVT STAFLAELLS SNVVNDLMLL ESLLYNLMAR QKDTSARVRR LVLHGLANIT
     LGSPDKVQTH SPQLLTAMIG GLDDGDDPHS LVALEAMVGL ARLMDLVDAW DLHAVLLHIA
     VRIRPFFDSE RMELRSVSIG LFGHLNKACR GDCKDVFLEQ VVGGLVPLLL HLRDPHAPVV
     TACRFALRMC GPNLECEELA AVFQRHLQEG HDLHFGEFLN TTCKHLMRHF PDLLGRLLST
     SLFYYKSSWE DVRAAAPMLT GFLVLHMEAE QRPQVDLEQL LTALQLLLKD PALKVRLKAV
     KTLGRLVKFA
//