ID F1MMA0_BOVIN Unreviewed; 899 AA.
AC F1MMA0;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 3.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Interleukin enhancer binding factor 3 {ECO:0000313|Ensembl:ENSBTAP00000018818.6};
GN Name=ILF3 {ECO:0000313|Ensembl:ENSBTAP00000018818.6,
GN ECO:0000313|VGNC:VGNC:30176};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000018818.6, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000018818.6, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000018818.6,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000018818.6}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000018818.6};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; NP_001193424.1; NM_001206495.1.
DR AlphaFoldDB; F1MMA0; -.
DR SMR; F1MMA0; -.
DR STRING; 9913.ENSBTAP00000018818; -.
DR PaxDb; 9913-ENSBTAP00000018818; -.
DR Ensembl; ENSBTAT00000018818.6; ENSBTAP00000018818.6; ENSBTAG00000040076.4.
DR GeneID; 614936; -.
DR KEGG; bta:614936; -.
DR CTD; 3609; -.
DR VEuPathDB; HostDB:ENSBTAG00000040076; -.
DR VGNC; VGNC:30176; ILF3.
DR eggNOG; KOG3792; Eukaryota.
DR GeneTree; ENSGT00940000156719; -.
DR HOGENOM; CLU_015490_0_0_1; -.
DR InParanoid; F1MMA0; -.
DR OMA; PANHTQY; -.
DR OrthoDB; 4565640at2759; -.
DR TreeFam; TF320194; -.
DR Reactome; R-BTA-9762293; Regulation of CDH11 gene transcription.
DR Reactome; R-BTA-9833482; PKR-mediated signaling.
DR Proteomes; UP000009136; Chromosome 7.
DR Bgee; ENSBTAG00000040076; Expressed in granulosa cell and 108 other cell types or tissues.
DR ExpressionAtlas; F1MMA0; baseline and differential.
DR GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:Ensembl.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003725; F:double-stranded RNA binding; IBA:GO_Central.
DR GO; GO:0035925; F:mRNA 3'-UTR AU-rich region binding; IEA:Ensembl.
DR GO; GO:0003727; F:single-stranded RNA binding; IBA:GO_Central.
DR GO; GO:0001618; F:virus receptor activity; IEA:Ensembl.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:Ensembl.
DR GO; GO:0017148; P:negative regulation of translation; IEA:Ensembl.
DR GO; GO:0045071; P:negative regulation of viral genome replication; IEA:Ensembl.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:Ensembl.
DR CDD; cd19910; DSRM_ILF3_rpt1; 1.
DR CDD; cd19912; DSRM_ILF3_rpt2; 1.
DR Gene3D; 1.10.1410.40; -; 1.
DR Gene3D; 3.30.160.20; -; 2.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 2.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR033099; DSRM1_ILF3.
DR InterPro; IPR006561; DZF_dom.
DR InterPro; IPR049402; DZF_dom_C.
DR InterPro; IPR049401; DZF_dom_N.
DR InterPro; IPR043519; NT_sf.
DR PANTHER; PTHR45762:SF4; INTERLEUKIN ENHANCER-BINDING FACTOR 3; 1.
DR PANTHER; PTHR45762; ZINC FINGER RNA-BINDING PROTEIN; 1.
DR Pfam; PF00035; dsrm; 2.
DR Pfam; PF20965; DZF_C; 1.
DR Pfam; PF07528; DZF_N; 1.
DR SMART; SM00358; DSRM; 2.
DR SMART; SM00572; DZF; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR PROSITE; PS50137; DS_RBD; 2.
DR PROSITE; PS51703; DZF; 1.
PE 4: Predicted;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00266}; Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 5..378
FT /note="DZF"
FT /evidence="ECO:0000259|PROSITE:PS51703"
FT DOMAIN 398..467
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 528..594
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 50..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 363..401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 638..664
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 722..899
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..399
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..524
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 744..800
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 808..899
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 899 AA; 95943 MW; 63694ED20F5EEB82 CRC64;
MRPVRIFVND DRHVMAKHSS VYPTQEELEA VQNMVSHTER ALKAVSDWID EQEKGSSDHA
ESENVDVPAE DEGKEGAGEQ KTEHMTRTLR GVMRVGLVAK GLLLKGDLDL ELVLLCKEKP
TTALLDKVAD NLAIQLTAVT DDKYEILQSV DDAAIVIKNT KEPPLSLTIH LTSPVVREEM
EKVLAGETLS VNDPPDVLDR QKCLAALASL RHAKWFQARA NGLKSCVIVI RVLRDLCTRV
PTWGPLRGWP LELLCEKSIG TANRPMGAGE ALRRVLECLA SGIVMPDGSG IYDPCEKEAT
DAIGHLDRQQ REDITQSAQH ALRLAAFGQL HKVLGMDPLP SKMPKKPKNE NPVDYTVQIP
PSTTYAITPM KRPMEEDGEE KSPSKKKKKI QKKEEKAEPP QAMNALMRLN QLKPGLQYKL
ISQTGPVHAP IFTMSVEVDG SSFEASGPSK KTAKLHVAVK VLQDMGLPTG AEGRDSSKGE
DSAEETEAKP AVVAPPPVVE TVSTPSAAFP SDPTTENVKQ QGPILTKHGK NPVMELNEKR
RGLKYELISE TGGSHDKRFV MEVEVDGQKF QGAGSNKKVA KAYAALAALE KLFPDAPLSL
EANKKKRAPV PVRGGPKFAA KPHNPGFGMG GPMHNEVPPP PNLRGRGRGG NIRGRGRGRG
FGGANHGGYM NAGAGYGSYG YGGNSATAGY SQFYSNGGHS GNAGGGGGGG GGGSSGYGSY
YQGDNYNSPV PPKHAGKKQP HGGQQKPSYG SGYQPHQGQQ QSYSQSQYSN YGPPQGKQKG
YNHGQGNYSS YSNSYGSPGG GGGSDYSYES KFNYSGSGGR SGGNSYGSGG SSYNPGSHGG
YGGSGGSSSY QGKQGGYSSQ SNYNSPGSGQ NYSGPPSSYQ SSQGGYGRNA DHSMNYQYR
//
