ID   F1MN55_BOVIN            Unreviewed;       559 AA.
AC   F1MN55;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 3.
DT   27-MAR-2024, entry version 60.
DE   SubName: Full=Transmembrane anterior posterior transformation 1 {ECO:0000313|Ensembl:ENSBTAP00000025911.6};
GN   Name=TAPT1 {ECO:0000313|Ensembl:ENSBTAP00000025911.6,
GN   ECO:0000313|VGNC:VGNC:35601};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000025911.6, ECO:0000313|Proteomes:UP000009136};
RN   [1] {ECO:0000313|Ensembl:ENSBTAP00000025911.6, ECO:0000313|Proteomes:UP000009136}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000025911.6,
RC   ECO:0000313|Proteomes:UP000009136};
RA   Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA   Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA   Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT   "ARS-UCD1.2.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSBTAP00000025911.6}
RP   IDENTIFICATION.
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000025911.6};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TAPT1 family.
CC       {ECO:0000256|ARBA:ARBA00008803}.
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DR   AlphaFoldDB; F1MN55; -.
DR   STRING; 9913.ENSBTAP00000025911; -.
DR   PaxDb; 9913-ENSBTAP00000025911; -.
DR   Ensembl; ENSBTAT00000025911.6; ENSBTAP00000025911.6; ENSBTAG00000019451.6.
DR   VEuPathDB; HostDB:ENSBTAG00000019451; -.
DR   VGNC; VGNC:35601; TAPT1.
DR   eggNOG; KOG2490; Eukaryota.
DR   GeneTree; ENSGT00390000010628; -.
DR   HOGENOM; CLU_003655_3_0_1; -.
DR   InParanoid; F1MN55; -.
DR   OMA; QPTHQKE; -.
DR   TreeFam; TF105962; -.
DR   Proteomes; UP000009136; Chromosome 6.
DR   Bgee; ENSBTAG00000019451; Expressed in neutrophil and 105 other cell types or tissues.
DR   GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR   GO; GO:0036064; C:ciliary basal body; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEA:UniProtKB-KW.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0045724; P:positive regulation of cilium assembly; IBA:GO_Central.
DR   InterPro; IPR008010; Tatp1.
DR   PANTHER; PTHR13317:SF4; TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG; 1.
DR   PANTHER; PTHR13317; UNCHARACTERIZED; 1.
DR   Pfam; PF05346; DUF747; 1.
PE   3: Inferred from homology;
KW   Chondrogenesis {ECO:0000256|ARBA:ARBA00023188};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Osteogenesis {ECO:0000256|ARBA:ARBA00022855};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        158..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        238..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        400..417
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        423..448
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          464..542
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..27
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        474..520
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        521..542
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   559 AA;  63479 MW;  2149C8CCEF40BEDD CRC64;
     MAGVGDAAAP REGGADGAER DGRAEAEQLG GGGHGPPPAP QHTETLGFYE SDRRRERRRS
     RAELSLFRFL SAELTRGYFL EHNEAKYTER RERVYTCMRI PRELEKLMVF GIFLCLDAFL
     YVFTLLPVRV FLALFRLFTL PCYGLRDRRV LQPAQVCDVL KGVILVICYC MMHYVDYSMM
     YHLIRGQSVI KLYIIYNMLE VADRLFSSFG QDILDALYWT ATEPKERRRA HIGVAPHFFM
     AVLYVFLHAI LIMVQATTLN VAFNSHNKSL LTIMMSNNFV EIKGSVFKKF EKNNLFQMSN
     SDIKERFTNY VLLLIVCLRN MEQFSWNPDH LWVLFPDVCM VVASEIAVDI VKHAFITKFN
     DITADVYSEY RASLAFDLVS SRQKNAYTDY SDSVARRMGF IPLPLAVLLI RVVTSSVKVQ
     GILSYACVIL FYLGLISLKV LNSIVLLGKS CQYVKEAKME DKLFNPPPAS APGKPSSKSQ
     NKCKSSQEET LSASVTSQPT HQKENAIPLL VTSSSDQLLT TPDGDEKDIT QENSELKHRS
     SKKDLLEVDR FTICGNRID
//