ID F1MPG9_BOVIN Unreviewed; 756 AA.
AC F1MPG9;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 2.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Pleckstrin homology domain containing M3 {ECO:0000313|Ensembl:ENSBTAP00000010299.5};
GN Name=PLEKHM3 {ECO:0000313|Ensembl:ENSBTAP00000010299.5,
GN ECO:0000313|VGNC:VGNC:54470};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000010299.5, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000010299.5, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000010299.5,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000010299.5}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000010299.5};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; NP_001193146.1; NM_001206217.1.
DR AlphaFoldDB; F1MPG9; -.
DR SMR; F1MPG9; -.
DR STRING; 9913.ENSBTAP00000010299; -.
DR PaxDb; 9913-ENSBTAP00000010299; -.
DR Ensembl; ENSBTAT00000010299.5; ENSBTAP00000010299.5; ENSBTAG00000007830.5.
DR GeneID; 533312; -.
DR KEGG; bta:533312; -.
DR CTD; 389072; -.
DR VEuPathDB; HostDB:ENSBTAG00000007830; -.
DR VGNC; VGNC:54470; PLEKHM3.
DR eggNOG; KOG1829; Eukaryota.
DR GeneTree; ENSGT00940000159743; -.
DR HOGENOM; CLU_021585_0_0_1; -.
DR InParanoid; F1MPG9; -.
DR OMA; CELCHNG; -.
DR OrthoDB; 126314at2759; -.
DR TreeFam; TF317067; -.
DR Proteomes; UP000009136; Chromosome 2.
DR Bgee; ENSBTAG00000007830; Expressed in neutrophil and 107 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd14674; PH_PLEKHM3_1; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR037812; PLEKHM3_PH_1.
DR InterPro; IPR025258; RH_dom.
DR PANTHER; PTHR12326; PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12326:SF10; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 3; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF13901; RH_dom; 1.
DR SMART; SM01175; DUF4206; 1.
DR SMART; SM00233; PH; 2.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 356..451
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
SQ SEQUENCE 756 AA; 86314 MW; 7BAFE54949542A4E CRC64;
MEALEVDDIS PALEVTEDFF NTFDNKLEKA VQQAEVYGIQ EVPELVGREV LGNIDNGAIR
NVTSLGQGGV IWDHCKTRLL DTKVPNVFPA KEQFMVQKGT TPDNLSWMEQ KEASTFNFFN
ICQRRRDRPR SVNDLLDETS TFKPGHARSR SDITQVDWRV VLKTMPLQQE VSLQGPHFAR
PSLLLSSSNK VEDAQGNTEH KPAFPNILKK GYLEIRKEHD SYWQSCYAEL SPYSLYFYSL
DSSGNQNLYA TYQLSHFQSI SVLGNLEARL VDTVLYDNTQ LQLKAESPWE ALDWGQKLWE
GVHAAAPAYM GRPGELANSP GLGHHVDCPQ NHCLQKKSRE LLMPSPVLDS PKQYQNILKS
GTLYRLTMQN NWKAFTFVLS RTCLMAFPPG KLDEDPLLSY NVDVCLAVQL DHLDDCDSCF
QVIFPQDVLR LRAETRQRAQ EWMEALKTAA NTARSSEQNL QVTLRTKPRD QMGGHELRKN
KRQSVTTSFL SILTTLSLER GLTAQSFKCA GCQRSIGLSN GKAKVCSYSG WYYCSSCHVD
DSFLIPARIV HNWDTSKYKV SKQAKEFLEY VYEEPLIDIQ QQNPMLYGHA EPLATVVRLR
QRLKSLRAYL FSCRAAVAED LRRRIFPREY LLQQIHLYSL ADLQQVIEGK LAPFLGKVIK
FATSHVYSCS LCSQKGFICE ICNNGEILYP FEDISTSRCE SCGAVFHAEC KEKSVPCPRC
VRRELQMKQK SFWRRLNMDE SLEEACNMFE LSYQNT
//
