ID   F1N101_BOVIN            Unreviewed;      1399 AA.
AC   F1N101;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 3.
DT   27-MAR-2024, entry version 80.
DE   SubName: Full=Uveal autoantigen with coiled-coil domains and ankyrin repeats {ECO:0000313|Ensembl:ENSBTAP00000018584.6};
GN   Name=UACA {ECO:0000313|Ensembl:ENSBTAP00000018584.6,
GN   ECO:0000313|VGNC:VGNC:36558};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000018584.6, ECO:0000313|Proteomes:UP000009136};
RN   [1] {ECO:0000313|Ensembl:ENSBTAP00000018584.6, ECO:0000313|Proteomes:UP000009136}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000018584.6,
RC   ECO:0000313|Proteomes:UP000009136};
RA   Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA   Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA   Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT   "ARS-UCD1.2.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSBTAP00000018584.6}
RP   IDENTIFICATION.
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000018584.6};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   Ensembl; ENSBTAT00000018584.6; ENSBTAP00000018584.6; ENSBTAG00000013982.6.
DR   VEuPathDB; HostDB:ENSBTAG00000013982; -.
DR   VGNC; VGNC:36558; UACA.
DR   GeneTree; ENSGT00940000157475; -.
DR   TreeFam; TF331274; -.
DR   Proteomes; UP000009136; Chromosome 10.
DR   Bgee; ENSBTAG00000013982; Expressed in surface of tongue and 104 other cell types or tissues.
DR   ExpressionAtlas; F1N101; baseline and differential.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   PANTHER; PTHR24129; ANKYCORBIN; 1.
DR   PANTHER; PTHR24129:SF2; UVEAL AUTOANTIGEN WITH COILED-COIL DOMAINS AND ANKYRIN REPEATS; 1.
DR   Pfam; PF12796; Ank_2; 2.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 6.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   SUPFAM; SSF90257; Myosin rod fragments; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 4.
DR   PROSITE; PS50088; ANK_REPEAT; 5.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          54..86
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          87..119
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          120..152
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          153..185
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          186..218
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   COILED          276..359
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          461..495
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          522..584
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          612..646
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          688..715
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          758..823
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          859..1366
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1399 AA;  161155 MW;  75213017AA47E96F CRC64;
     MMSCWFSCAP KNRQAADWNK YDDRLMKAAE RGDVEKVSSI LAKKGVNPGK LDVEGRSAFH
     VVASKGNLEC LNAILIHGVD ITTSDTAGRN ALHLAAKYGH ALCLQKLLQY NCPTEHVDLQ
     GRTALHDAAM ADCPSSIQLL CDHGASVNAK DVDGRTPLVL ATQMCRPTIC QLLIDRGADI
     NSRDKQNRTA LMLGCEYGCK DAVEVLIKNG ADVTLLDALG HDSSYYARIG DNLDILTLLK
     TASENSNKGR ELWKKGPSLQ QRNLSQMLDE VNTKSNQREH QNIQDLEIEN EDLKERLRKI
     QQEQRILLDK VNGLQLQLNE EVMVADDLES EKEKLKSLLA AKEKQHEESL RTIEALKSRF
     KYFEVSFIWI YLGKEDMLLK QGQMYMTDSQ CTSTGMPVHM QSRSMLRPLE LALPNQASYS
     ENEILKKELE AMRTFCDSAK QDRLKLQNEL AHKVAECKAL ALECERVKED SDEQIKQLED
     ALKDVQKRMY ESEGKVKQMQ THFLALKEHL TSDAATGNHR LMEELKDQLK DMKVKYEGAS
     AEVGKLRNQI KQNEMLVEEF KRDEGKLMEE NKRLQKELSM CELEREKRGR KLTEMEGQLK
     DLSAKLALSI PAEKFENMKS LLSNELNEKA KKLIDVEREY ERSLNETRPL KRELENLKAK
     LAQHVKPEEH EQLKSRLEQK SGELGKRITE LTSKNQTLQK EIEKVCLDNK LLTQQVNNLT
     TEMKNHYVPL KVSEEMKKSH DVIVDDLNKK LSDVTHKYTE KKLEMEKLLM ENASLSKNVS
     RLETVFIPPE RHEKEMMALK SNITELKKQL SELNKKCGED QEKIYSLMSE NNDLKKTMSH
     QYVPVKTHEE IKTALSSTLD KTNRELVDVK KKCEDINQEF VKIKDENEIL KRNLENTQNQ
     VKAEYISLRE HEEKMSGLRK SMKKVQDNSA EILANYKKSQ EEIVTLHEEI AAQKRELDTI
     QECIKLKYAP IISLEECERK FKATEKELKE QLSQQTQKYN TSEEEAKKCK QENDKLKKEI
     LTLQKDLKDK NVHIENSYET ERALSRKTEE LNRQLKDLLQ KYTEAKKEKE KLVEENAKQT
     SEILAAQTLL QKQHVPLEQV ESLKKSLSGT IETLKEELKT KQRCYEKEQQ TVTQLRQMLE
     NQKNSSVPLA EHLQVKEAFE KEVGIIKASL REKEEESQNK TEEVSKLQSE IQNTKQALKK
     LETREVVDLS KYKATKSDLE TQISDLNEKL ANLNRKYEEV CEEVLHAKKK ELSAKDEKEL
     LHFSIEQEIK DQQERCDKSL TTITELQRRI QESAKQIEAK DNKITELLND VERLKQALNG
     LSQLTYGSGS PSKRQSQLID SLQQQVRSLQ QQLADADRQH QEVIAIYRTH LLSAAQGHMD
     EDVQAALLQI IQMRQGLVC
//