ID F1Q8T6_DANRE Unreviewed; 693 AA.
AC F1Q8T6; A0A8M1RL95;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=SITS-binding protein {ECO:0000313|RefSeq:XP_002666900.3};
DE SubName: Full=Si:ch211-236l14.4 {ECO:0000313|Ensembl:ENSDARP00000083711};
GN Name=si:ch211-236l14.4 {ECO:0000313|Ensembl:ENSDARP00000083711,
GN ECO:0000313|RefSeq:XP_002666900.3,
GN ECO:0000313|ZFIN:ZDB-GENE-081104-189};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000083711};
RN [1] {ECO:0000313|Ensembl:ENSDARP00000083711}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000083711};
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSDARP00000083711, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000083711};
RX PubMed=23594743; DOI=10.1038/nature12111;
RG Genome Reference Consortium Zebrafish;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D.,
RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B.,
RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M.,
RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M.,
RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J.,
RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D.,
RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K.,
RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R.,
RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M.,
RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M.,
RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M.,
RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D.,
RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J.,
RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I.,
RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B.,
RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P.,
RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R.,
RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I.,
RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H.,
RA Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [3] {ECO:0000313|RefSeq:XP_002666900.3}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|RefSeq:XP_002666900.3};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AL928941; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BX248085; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CR392336; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_002666900.3; XM_002666854.6.
DR STRING; 7955.ENSDARP00000083711; -.
DR PaxDb; 7955-ENSDARP00000083711; -.
DR Ensembl; ENSDART00000089278; ENSDARP00000083711; ENSDARG00000062059.
DR Ensembl; ENSDART00000089278.6; ENSDARP00000083711.4; ENSDARG00000062059.7.
DR GeneID; 797251; -.
DR KEGG; dre:797251; -.
DR AGR; ZFIN:ZDB-GENE-081104-189; -.
DR ZFIN; ZDB-GENE-081104-189; si:ch211-236l14.4.
DR eggNOG; KOG1065; Eukaryota.
DR HOGENOM; CLU_008294_0_0_1; -.
DR OMA; QLIPVMS; -.
DR OrthoDB; 2725689at2759; -.
DR PhylomeDB; F1Q8T6; -.
DR TreeFam; TF324266; -.
DR Proteomes; UP000000437; Chromosome 25.
DR Bgee; ENSDARG00000062059; Expressed in muscle tissue and 8 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR048395; Glyco_hydro_31_C.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR43053; GLYCOSIDASE FAMILY 31; 1.
DR PANTHER; PTHR43053:SF6; SITS-BINDING PROTEIN; 1.
DR Pfam; PF21365; Glyco_hydro_31_3rd; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 606..690
FT /note="Glycosyl hydrolase family 31 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21365"
SQ SEQUENCE 693 AA; 78921 MW; 7EFE706A94C38970 CRC64;
MPHTRNRNPS PIPEVTWDTG LKEMNETWKG AIACLGVAVF FVMTIGIIYW QVVDQPNKNW
ILKGSFSGLI WERRTQTLVI QTLTEDKTFA EIDVENVGNT DIEVPFVRNM CWLNKTEFCY
TWDSVAEVKI SLESEEDSDT ECYSVTWTPI HCHVDLKDCF SMVNISWYGG ASVRAPNWPI
NNANISMQPF TVSDFRDNPS GFGSVLERYF LGSSGVSVLV APNIPLHVGM ESQQQFCLQT
PPSMERMPLQ YTVCVGHNIK VVHQESMRQL STIRRELPNM DVLRLPFWKL LANVDSGAKL
ERELRTFSNR LKRHHLGEGI ISLDEHSTTL LTNMDHSYLN GKKRTSKRQT RDLPFVKLLN
ISITLSPYLS VDTQQFQTSI QEGIEDYWLS LPSGPQGQLV PLLTRWKGKY SVKLNITNPE
ATTWFLDKVD SLHSHLGMEY VILEGGEGNP FEEQALRPPL ELVGDEYIRL LADLAERIGD
NAIVTSGTRS SHKPLFIRMS ALQSDWSYSG LKGIIPSLLH HSLLGYNFFI PDAVGGSLSP
ELVGDDELFI RWLGIAAFLP VISFQTPPWV FEKEWVLNLT RFYIAKHHDF VVPLILKYAD
EWQETGNPIY RPLWWLSPND PITFSIDDEF LIGDEVLVAP VTEKGSLHRD IYLPESDFQW
LDTNNAQVFD GGTFLENYSV GLGDVPVFVQ WRP
//
