ID F1RT25_PIG Unreviewed; 140 AA.
AC F1RT25;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 4.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Sorting nexin 3 {ECO:0000313|Ensembl:ENSSSCP00000004733.4};
GN Name=SNX3 {ECO:0000313|Ensembl:ENSSSCP00000004733.4,
GN ECO:0000313|VGNC:VGNC:93317};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000004733.4, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000004733.4, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000004733.4,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000004733.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Early endosome {ECO:0000256|ARBA:ARBA00004412}.
CC Endosome {ECO:0000256|ARBA:ARBA00004177}.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR AlphaFoldDB; F1RT25; -.
DR SMR; F1RT25; -.
DR PeptideAtlas; F1RT25; -.
DR Ensembl; ENSSSCT00000004847.5; ENSSSCP00000004733.4; ENSSSCG00000004385.5.
DR VGNC; VGNC:93317; SNX3.
DR eggNOG; KOG2527; Eukaryota.
DR GeneTree; ENSGT00940000153609; -.
DR HOGENOM; CLU_057172_2_2_1; -.
DR TreeFam; TF314980; -.
DR Proteomes; UP000008227; Chromosome 1.
DR Bgee; ENSSSCG00000004385; Expressed in Ammon's horn and 45 other cell types or tissues.
DR ExpressionAtlas; F1RT25; baseline and differential.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR45963; RE52028P; 1.
DR PANTHER; PTHR45963:SF1; SORTING NEXIN-3; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 1: Evidence at protein level;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Proteomics identification {ECO:0007829|PeptideAtlas:F1RT25};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT DOMAIN 1..129
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
SQ SEQUENCE 140 AA; 16316 MW; 01710ACF7D256DCA CRC64;
MAETVADTRR LITKPQNLND AYGPPSNFLE IDTNLPIFKL KESTVRRRYS DFEWLRSELE
RESKVVVPPL PGKAFLRQLP FRGDDGIFDD NFIEERKQGL EQFINKVAGH PLAQNERCLH
MFLQDEIIDK SYTPSKIRHA
//
